|
| Status |
Public on May 28, 2020 |
| Title |
Microarray analysis of c-Jun/JunB knockout mice treated with dithranol |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Ears of c-Jun/JunB knockout mice were topically treated with dithranol
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| |
|
| Overall design |
Mice carrying floxed alleles for the JunB and c-Jun locus and expressing the K5-CreERT transgene received consecutive i.p. injections of tamoxifen for a period of 5 days, leading to deletion of both genes in the epidermis by inducible Cre-recombinase activity. One week after the last injection, psoriasis-like lesions on the ears were treated daily with vehicle (Vaseline) or dithranol in series of increasing concentrations.
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| |
|
| Contributor(s) |
Benezeder T, Wolf P |
| Citation(s) |
32484435 |
| Submission date |
Feb 11, 2020 |
| Last update date |
Jun 08, 2020 |
| Contact name |
Karin Wagner |
| E-mail(s) |
kar.wagner@medunigraz.at
|
| Organization name |
Medical University Graz
|
| Department |
Molecular Biology
|
| Street address |
Stiftingtalstrasse 24
|
| City |
Graz |
| State/province |
Styria |
| ZIP/Postal code |
8010 |
| Country |
Austria |
| |
|
| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA606083 |
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