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Series GSE146508 Query DataSets for GSE146508
Status Public on May 20, 2020
Title Transcriptome and open chromatin analysis of 5-month mouse liver and blood by the TaRGET II consortium
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary The TaRGET (Toxicant Exposures and Responses by Genomic and Epigenomic Regulators of Transcription) program is a research consortium funded by the National Institute of Environmental Health Sciences (NIEHS). The goal of the collaboration is to address the role of environmental exposures in disease pathogenesis as a function of epigenome perturbation, including understanding the environmental control of epigenetic mechanisms and assessing the utility of surrogate tissue analysis in mouse models of disease-relevant environmental exposures (https://targetepigenomics.org).
 
Overall design RNA-seq and ATAC-seq of liver and blood samples from 5-month mice that were subjected to disease-relevant environmental exposures.
The TaRGET II consortium (https://targetepigenomics.org/about/)
 
Citation(s) 29509741
Submission date Mar 06, 2020
Last update date Sep 27, 2020
Contact name Daofeng Li
E-mail(s) lidaof@gmail.com
Phone (314) 286-0866
Organization name Washington University in St. Louis
Department Genetics
Lab Ting Wang Lab
Street address 4515 McKinley Avenue
City SAINT LOUIS
State/province MO
ZIP/Postal code 63110
Country USA
 
Platforms (6)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
GPL19057 Illumina NextSeq 500 (Mus musculus)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (849)
GSM4387308 Aylor_ATAC_Blood_Ctrl_5month_Female_biorep1
GSM4387309 Aylor_ATAC_Blood_Ctrl_5month_Female_biorep2
GSM4387310 Aylor_ATAC_Blood_Ctrl_5month_Female_biorep3
Relations
BioProject PRJNA610793
SRA SRP251846

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Supplementary file Size Download File type/resource
GSE146508_RAW.tar 896.2 Mb (http)(custom) TAR (of CSV, NARROWPEAK)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
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