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| Status |
Public on May 01, 2021 |
| Title |
SATB1 promotion of trophoblast stem cell renewal |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Trophoblast stem (TS) cell renewal and differentiation are essential processes in placentation. Here, we have identified the mechanism/targets of chromatin organizer/transcription factor called special AT-rich binding protein 1 (SATB1) action on TS cell renewal by RNA-seq analysis in Rcho-1 TS cells expressing Satb1 shRNAs.
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| Overall design |
Rcho-1 TS cells transduced with control shRNAs were used as controls. Cells transduced with two different shRNAs targeting Satb1 were used as treatment. RNA-seq was performed in TS cells at 4 days (acute) and 10 days (chronic) after transduction.
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| Contributor(s) |
Kubota K, Iqbal K, Soares MJ |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jun 01, 2020 |
| Last update date |
May 01, 2021 |
| Contact name |
Khursheed Iqbal |
| E-mail(s) |
kiqbal@kumc.edu
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| Phone |
913 588 5690
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| Organization name |
University of Kansas Medical Center
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| Department |
Pathology
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| Street address |
3901 Rainbow Blvd
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| City |
Kansas City |
| State/province |
Kansas |
| ZIP/Postal code |
66160 |
| Country |
USA |
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| Platforms (1) |
| GPL14844 |
Illumina HiSeq 2000 (Rattus norvegicus) |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA636379 |
| SRA |
SRP265496 |
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