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| Status |
Public on Jul 03, 2020 |
| Title |
T-cell acute lymphobalstic leukemia xenografts in NOD/SCID mouse |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Gene expression analysis of twenty patient-derived T-ALL xenografts was performed to determine if a GLI activation signature was enriched in GANT-61 sensitive cells.
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| Overall design |
Gene expression analysis of twenty patient-derived T-ALL xenografts using cells obtained from the spleens of diseased mice. Cells obtained from independent mice were evaluated in vitro for their sensitivity to the GLI inhibitor, GANT-61.
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| Contributor(s) |
Piovan E, Milani G, van Vlierberghe P, Minuzzo S, Indraccolo S |
| Citation(s) |
32733009 |
| Submission date |
Jul 02, 2020 |
| Last update date |
Aug 03, 2020 |
| Contact name |
Erich Piovan |
| E-mail(s) |
erich.piovan@unipd.it
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| Organization name |
University of Padua
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| Department |
Dep. Surgery, Oncology and Gastroenterology
|
| Street address |
via Gattamelata 64
|
| City |
Padua |
| ZIP/Postal code |
35128 |
| Country |
USA |
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| Platforms (1) |
| GPL14550 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Probe Name Version) |
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| Samples (20)
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| This SubSeries is part of SuperSeries: |
| GSE153750 |
Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination |
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| Relations |
| BioProject |
PRJNA643797 |
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