|
| Status |
Public on Jul 08, 2021 |
| Title |
Regnase-1 KO CAR T cell reprogramed to memory-like cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
transcriptional profiling was performed on WT and KO CAR T cells isolated 21 days after co-transfer into tumor bearing mice.
Regnase-1 KO CAR T cell reprogramed to memory-like cells long-term after tumor priming in vivo compared to WT CAR T cells
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| |
|
| Overall design |
In total 6 samples were analyzed: (WT CAR n=3; KO CAR n=3)
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| |
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| Contributor(s) |
Wenting Z, Dhungana Y, Terrence G |
| Citation(s) |
33690816 |
| Submission date |
Jul 22, 2020 |
| Last update date |
Jul 10, 2021 |
| Contact name |
Hongbo Chi |
| E-mail(s) |
hongbo.chi@stjude.org
|
| Organization name |
St Jude Children's Research Hospital
|
| Department |
Immunology
|
| Street address |
262 Danny Thomas Place
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
|
| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE155021 |
Regnase-1 suppresses TCF-1+ precursor exhausted T cell formation to limit CAR T cell responses against ALL |
|
| Relations |
| BioProject |
PRJNA647914 |
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