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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jan 01, 2010 |
| Title |
Expression data from Foxl2 wild-type and mutant ovaries and testes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Foxl2 is a forkhead transcription factor expressed only in the female, but not in the male gonad. We have created mice homozygous mutant for the Foxl2 gene (KO) as well as mice carrying a conditional mutant Foxl2 allele (floxed).
The expression profiles of conventional Foxl2 knockout and wildtype ovaries were compared at P3, using the Affy Mouse Genome 430 2.0 Array. Adult wildtype and conditional mutant (Foxl2 floxed x RosaCre-EBD treated with tamoxifen) ovaries were compared to adult wildtype testes using the Affymetrix Mouse Gene 1.0 ST Array. Both experiments (KO/WT P3 and Mutant/WT/Testis Adult were also compared to each other.)
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| Overall design |
Ovaries from newborn (postnatal day 3) and adult (8 week old) mice were excised from the animal and RNA was prepared from whole ovaries (Adult testes were excised and RNA was isolated from 1/4 testis).
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| Contributor(s) |
Uhlenhaut H |
| Citation(s) |
20005806 |
| Submission date |
Jun 26, 2009 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Henriette Uhlenhaut |
| E-mail(s) |
henriette.uhlenhaut@embl.de, nuhlenhaut@salk.edu
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| Phone |
+496221387432
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| URL |
http://www.embl.org
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| Organization name |
EMBL
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| Department |
Developmental Biology Unit
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| Lab |
Treier
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| Street address |
Meyerhofstrasse 1
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| City |
Heidelberg |
| ZIP/Postal code |
69117 |
| Country |
Germany |
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| Platforms (2) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| GSM422391 |
Adult testis, wild-type, replicate 1 |
| GSM422392 |
Adult testis, wild-type, replicate 2 |
| GSM422393 |
Adult testis, wild-type, replicate 3 |
| GSM422394 |
Adult ovary, wild-type, replicate 1 |
| GSM422395 |
Adult ovary, wild-type, replicate 2 |
| GSM422396 |
Adult ovary, Foxl2 mutant, replicate 1 |
| GSM422397 |
Adult ovary, Foxl2 mutant, replicate 2 |
| GSM422398 |
Adult ovary, Foxl2 mutant, replicate 3 |
| GSM422399 |
Ovary at P3, wild-type, replicate 1 |
| GSM422400 |
Ovary at P3, wild-type, replicate 2 |
| GSM422401 |
Ovary at P3, Foxl2 KO, replicate 1 |
| GSM422402 |
Ovary at P3, Foxl2 KO, replicate 2 |
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| Relations |
| BioProject |
PRJNA117553 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE16853_RAW.tar |
65.7 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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