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Status |
Public on Mar 18, 2021 |
Title |
Transcriptomic analysis of acquired resistance to a novel trimethoprim-based photoswitchable antibiotic in Escherichia coli CS1562 |
Organism |
Escherichia coli |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Effect of three different antimicrobial compounds, trimethoprim(TMP), cis-tetra-ortho-chloroazobenzene-trimethoprim (TCATa) and trans-tetra-ortho-chloroazobenzene-trimethoprim (TCATd) , on the resistance development and transcriptome of the E. coli strain CS1562. In addition, acontrol sample was taken along of the propagated parent strain (CS1562) without the addition of any compounds.
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Overall design |
4 samples; no replicates
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Contributor(s) |
Lauxen AI, Kobauri P, Galenkamp NS, Maglia G, Szymanski W, Feringa BL, Kuipers OP |
Citation(s) |
33919397 |
Submission date |
Mar 17, 2021 |
Last update date |
Jun 03, 2021 |
Contact name |
Anne de Jong |
E-mail(s) |
anne.de.jong@rug.nl
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Phone |
+31 50 363 2047
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Organization name |
university of Groningen
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Department |
Molecular Genetics
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Street address |
Nijenborgh 7
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City |
Groningen |
ZIP/Postal code |
9747 AG |
Country |
Netherlands |
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Platforms (1) |
GPL14548 |
Illumina HiSeq 2000 (Escherichia coli) |
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Samples (4)
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Relations |
BioProject |
PRJNA715103 |
SRA |
SRP311033 |
Supplementary file |
Size |
Download |
File type/resource |
GSE169069_RAW.tar |
270.0 Kb |
(http)(custom) |
TAR (of TXT) |
SRA Run Selector |
Raw data are available in SRA |
Processed data provided as supplementary file |
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