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Series GSE169069 Query DataSets for GSE169069
Status Public on Mar 18, 2021
Title Transcriptomic analysis of acquired resistance to a novel trimethoprim-based photoswitchable antibiotic in Escherichia coli CS1562
Organism Escherichia coli
Experiment type Expression profiling by high throughput sequencing
Summary Effect of three different antimicrobial compounds, trimethoprim(TMP), cis-tetra-ortho-chloroazobenzene-trimethoprim (TCATa) and trans-tetra-ortho-chloroazobenzene-trimethoprim (TCATd) , on the resistance development and transcriptome of the E. coli strain CS1562. In addition, acontrol sample was taken along of the propagated parent strain (CS1562) without the addition of any compounds.
 
Overall design 4 samples; no replicates
 
Contributor(s) Lauxen AI, Kobauri P, Galenkamp NS, Maglia G, Szymanski W, Feringa BL, Kuipers OP
Citation(s) 33919397
Submission date Mar 17, 2021
Last update date Jun 03, 2021
Contact name Anne de Jong
E-mail(s) anne.de.jong@rug.nl
Phone +31 50 363 2047
Organization name university of Groningen
Department Molecular Genetics
Street address Nijenborgh 7
City Groningen
ZIP/Postal code 9747 AG
Country Netherlands
 
Platforms (1)
GPL14548 Illumina HiSeq 2000 (Escherichia coli)
Samples (4)
GSM5176039 C
GSM5176040 TMP
GSM5176041 TCATa
Relations
BioProject PRJNA715103
SRA SRP311033

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE169069_RAW.tar 270.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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