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Status |
Public on Jun 27, 2022 |
Title |
Profiling of Gata1 binding in primary erythroid cells by CUT&RUN |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
The chromatin landscape of developing erythroblasts changes dramatically during differentiation. We have profiled the change in Gata1 binding in primary erythroid cells entering terminal differentiation using CUT&RUN.
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Overall design |
This series contains CUT&RUN datasets for Gata1 binding in FACS sorted primary erythroid cells. There are multiple biological replicates for each progenitor population, plus IgG control datasets.
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Contributor(s) |
Beagrie RA, Higgs DR |
Citation missing |
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Submission date |
Apr 02, 2021 |
Last update date |
Jun 30, 2022 |
Contact name |
Robert A Beagrie |
E-mail(s) |
robert.beagrie@ndcls.ox.ac.uk
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Organization name |
MRC Weatherall Institute of Molecular Medicine
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Department |
Molecular Haematology Unit
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Street address |
Headley Way
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City |
Oxford |
ZIP/Postal code |
OX39DS |
Country |
United Kingdom |
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Platforms (1) |
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Samples (17)
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GSM5224716 |
RB-CR62_Lin+ - Gata1 CUT&RUN replicate 1 |
GSM5224717 |
RB-CR71_Lin+ - Gata1 CUT&RUN replicate 2 |
GSM5224718 |
RB-CR63_S0 CD71 low - Gata1 CUT&RUN replicate 1 |
GSM5224719 |
RB-CR72_S0 CD71 low - Gata1 CUT&RUN replicate 2 |
GSM5224720 |
RB-CR64_S0 CD71 medium - Gata1 CUT&RUN replicate 1 |
GSM5224721 |
RB-CR73_S0 CD71 medium - Gata1 CUT&RUN replicate 2 |
GSM5224722 |
RB-CR65_S1 - Gata1 CUT&RUN replicate 1 |
GSM5224723 |
RB-CR74_S1 - Gata1 CUT&RUN replicate 2 |
GSM5224724 |
RB-CR75_S1 - IgG CUT&RUN replicate 2 |
GSM5224725 |
RB-CR66_S2 - Gata1 CUT&RUN replicate 1 |
GSM5224726 |
RB-CR67_S3 - Gata1 CUT&RUN replicate 1 |
GSM5224727 |
RB-CR69_S3 - Gata1 CUT&RUN replicate 1 |
GSM5224728 |
RB-CR77_S3 - Gata1 CUT&RUN replicate 2 |
GSM5224729 |
RB-CR78_S3 - Gata1 CUT&RUN replicate 2 |
GSM5224730 |
RB-CR79_S3 - IgG CUT&RUN replicate 2 |
GSM5224731 |
RB-CR70_S4 - Gata1 CUT&RUN replicate 1 |
GSM5224732 |
RB-CR81_S4 - Gata1 CUT&RUN replicate 2 |
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Relations |
BioProject |
PRJNA719369 |
SRA |
SRP313233 |