|
Status |
Public on Jun 03, 2021 |
Title |
Effects of a pyrethroid pesticide deltamethrin on gene expression profiles in mouse neuroblastoma Neuro2a cell |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
|
Summary |
Pyrethroids are one of the most commonly used classes of synthetic pesticides detected from all individuals in every part of the world; however, the mechanisms underlying the neurotoxicity of pyrethroids were still remain unclear. To understand neurotoxic mechanisms of DM, we investigated transcriptome changes by exposure to a pyrethroid pesticide deltamethrin (DM) in the mouse neuroblastoma Neuro2a cell.
|
|
|
Overall design |
We compared the gene expression profiles of cells exposed to 30 µM DM or vehicle (0.1%DMSO) dossolved in medium for 24 hours. Quality of the RNA was analyzed using a Bioanalyzer 2100. Gene expression was analyzed by an Affymetrix GeneChip® system with a Clariom S Mouse array.
|
|
|
Contributor(s) |
Hirano T, Tabuchi Y |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
Submission date |
Jun 02, 2021 |
Last update date |
Jun 05, 2021 |
Contact name |
Tetsushi Hirano |
E-mail(s) |
thirano@cts.u-toyama.ac.jp
|
Organization name |
University of Toyama
|
Department |
Life Science Research Center
|
Street address |
2630 sugitani
|
City |
Toyama |
State/province |
Toyama |
ZIP/Postal code |
939 0194 |
Country |
Japan |
|
|
Platforms (1) |
GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
|
Samples (4)
|
|
Relations |
BioProject |
PRJNA734568 |