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| Status |
Public on Jun 05, 2021 |
| Title |
Differentially Expressed Mitochondrial Circulating mRNA in Hypothyroidism Could Be Useful as a Survivor Biomarker in Nonthyroidal Illness Syndrome |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
RNA libraries were constructed from whole blood. We called hypothyroidism differentially expressed genes with the Noiseq. We found a total of 4,197 transcripts regulated by the thyroid hormone present in the peripheral blood. We also found that three hundred and thirty-six (8.01%) were mitochondrial genes type.
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| Overall design |
It was constructed libraries of four subjects with TSH within reference range to compose the control (CTL) group and four hypothyroidism patients (HT).
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| Contributor(s) |
Almeida RJ, Hirata AH, Rocha LA, Motta MD, Varela P, Silva LM, Pesquero JB, Camacho CP |
| Citation(s) |
37249456 |
| Submission date |
Jun 04, 2021 |
| Last update date |
Dec 08, 2023 |
| Contact name |
Robson José de Almeida |
| Organization name |
Universidade Nove de Julho
|
| Department |
Pós Graduação Stricto Sensu em Medicina
|
| Lab |
Molecular Innovation and Biotechnology Laboratory
|
| Street address |
RUA VERGUEIRO 235 249
|
| City |
SAO PAULO |
| State/province |
SAO PAULO |
| ZIP/Postal code |
01504-001 |
| Country |
Brazil |
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| Platforms (1) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA735194 |
| SRA |
SRP322732 |
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