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| Status |
Public on Sep 23, 2021 |
| Title |
Transcriptomes of human myometrium in labor reveals the increased molecular associated with inflammation under hypoxia stress |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Labor involves a variety of coordinated events across physiological and biochemical aspects, the molecular mechanism responsible for the transition of the myometrium from the quiescent to a contractile state remains indistinct.The global transcriptome in human non-labor and in labor myometrium was investigated through RNA sequencing (RNA-seq) to explore biological processes and pathways alterations during labor. The transcriptomic bioinformatics results showed that the up-regulated mRNAs increased inflammation under hypoxia stress in laboring myometrium.
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| |
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| Overall design |
mRNA, lncRNA profiles of human myometrium in labor and non-labor
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| |
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| Contributor(s) |
Chen L, Liu H, Luo Y, Ji K |
| Citation(s) |
34671346, 35467262 |
| Submission date |
Aug 02, 2021 |
| Last update date |
Oct 27, 2022 |
| Contact name |
Kaiyuan Ji |
| E-mail(s) |
jky435@smu.edu.cn
|
| Organization name |
Guangzhou Medical University
|
| Department |
Guangzhou Women and Children’s Medical Center
|
| Lab |
Department of Obstetrics and Gynecology
|
| Street address |
No.9 Jinsui Road, Guangzhou, China
|
| City |
Guangzhou |
| ZIP/Postal code |
510623 |
| Country |
China |
| |
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| Platforms (1) |
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| Samples (25)
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| Relations |
| BioProject |
PRJNA751612 |
| SRA |
SRP330918 |
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