|
| Status |
Public on Jun 04, 2010 |
| Title |
Gene expression of colon from control or VilCre;Ihhflox/flox mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Ihh expression is required for intestinal stem cell niche development.
Loss of Ihh leads to disruption of intestinal stem cell niche, which leads to abnormal stem cell development and epithelial cell differentiation.
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| |
|
| Overall design |
3 paired control (C) and mutant (M) mice here harvested. Their colon tissues were analyzed using Affymetrix Mouse Gene 1.0ST array
Control and VilCre;Ihhflox/flox mice were harvested at p12
There are 3 pairs (total 6) samples:
M1 and C1 are littermates
M2 and C2 are littermates
M3 and C3 are littermates
|
| |
|
| Contributor(s) |
Chen X |
| Citation(s) |
20542037 |
| Submission date |
Oct 02, 2009 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Xin Chen |
| E-mail(s) |
xin.chen@ucsf.edu
|
| Phone |
(415) 502-6526
|
| Fax |
(415) 502-4332
|
| Organization name |
UCSF
|
| Street address |
|
| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94143-0446 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA118079 |
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