 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Mar 01, 2010 |
| Title |
Subpopulations of CD163 positive macrophages are classically activated in psoriasis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To determine the transcriptional profile associated with macrophage polarization to M1 or M2, we cultured macrophages derived from monocytes for 7 days and treated them with IFNg, IL-4, TNF, LPS, and LPS+IFNg (n=7). Psoriasis lesional and non-lesional skin biopsies were included (n=5 pairs).
|
| |
|
| Overall design |
Comparison of the transcriptome of psoriasis with cytokine-treated macrophages.
|
| |
|
| Contributor(s) |
Fuentes-Duculan J, Suarez-Farinas M |
| Citation(s) |
20555352 |
| Submission date |
Oct 22, 2009 |
| Last update date |
Aug 16, 2018 |
| Contact name |
Mayte Suarez-Farinas |
| E-mail(s) |
mayte.suarezfarinas@mssm.edu
|
| Organization name |
Mount SinaiSchool of Medicine
|
| Street address |
1425 Madison Ave, L2-70C, Box 1077,
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10075 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6947 |
Illumina HumanHT-12 V3.0 expression beadchip |
|
| Samples (58)
|
| GSM464204 |
Macrophage culture, ID 1, IL4 |
| GSM464205 |
Macrophage culture, ID 1, TNFa |
| GSM464206 |
Macrophage culture, ID 1, LPS |
| GSM464207 |
Macrophage culture, ID 1, LPSandIFNg |
| GSM464208 |
Macrophage culture, ID 2, Control |
| GSM464209 |
Macrophage culture, ID 2, IL17 |
| GSM464210 |
Macrophage culture, ID 2, IFNg |
| GSM464211 |
Macrophage culture, ID 2, IL4 |
| GSM464212 |
Macrophage culture, ID 2, TNFa |
| GSM464213 |
Macrophage culture, ID 2, LPS |
| GSM464214 |
Macrophage culture, ID 2, LPSandIFNg |
| GSM464215 |
Macrophage culture, ID 3, Control |
| GSM464216 |
Macrophage culture, ID 3, IL17 |
| GSM464217 |
Macrophage culture, ID 3, IFNg |
| GSM464218 |
Macrophage culture, ID 3, IL4 |
| GSM464219 |
Macrophage culture, ID 3, TNFa |
| GSM464220 |
Macrophage culture, ID 3, LPS |
| GSM464221 |
Macrophage culture, ID 3, LPSandIFNg |
| GSM464222 |
Macrophage culture, ID 4, Control |
| GSM464223 |
Macrophage culture, ID 4, IL17 |
| GSM464224 |
Macrophage culture, ID 4, IFNg |
| GSM464225 |
Macrophage culture, ID 4, IL4 |
| GSM464226 |
Macrophage culture, ID 4, TNFa |
| GSM464227 |
Macrophage culture, ID 4, LPS |
| GSM464228 |
Macrophage culture, ID 4, LPSandIFNg |
| GSM464229 |
Macrophage culture, ID 4, Control (rep) |
| GSM464230 |
Macrophage culture, ID 4, IL17 (rep) |
| GSM464231 |
Macrophage culture, ID 4, IFNg (rep) |
| GSM464232 |
Macrophage culture, ID 4, IL4 (rep) |
| GSM464233 |
Macrophage culture, ID 4, TNFa (rep) |
| GSM464234 |
Macrophage culture, ID 4, LPS (rep) |
| GSM464235 |
Macrophage culture, ID 4, LPSandIFNg (rep) |
| GSM464236 |
Macrophage culture, ID 5, Control |
| GSM464237 |
Macrophage culture, ID 5, IL17 |
| GSM464238 |
Macrophage culture, ID 5, IFNg |
| GSM464239 |
Macrophage culture, ID 5, IL4 |
| GSM464240 |
Macrophage culture, ID 5, TNFa |
| GSM464241 |
Macrophage culture, ID 5, LPS |
| GSM464242 |
Macrophage culture, ID 5, LPSandIFNg |
| GSM464243 |
Macrophage culture, ID 6, IL17 |
| GSM464244 |
Macrophage culture, ID 6, IFNg |
| GSM464245 |
Macrophage culture, ID 6, IL4 |
| GSM464246 |
Macrophage culture, ID 6, TNFa |
| GSM464247 |
Macrophage culture, ID 6, LPS |
| GSM464248 |
Macrophage culture, ID 6, LPSandIFNg |
| GSM464249 |
Psoriasis skin, ID P 001, NL |
| GSM464250 |
Psoriasis skin, ID P 002, LS |
| GSM464251 |
Psoriasis skin, ID P 003, NL |
| GSM464252 |
Psoriasis skin, ID P 004, LS |
| GSM464253 |
Psoriasis skin, ID P 005, NL |
| GSM464254 |
Psoriasis skin, ID P 006, LS |
| GSM464255 |
Psoriasis skin, ID P 007, NL |
| GSM464256 |
Psoriasis skin, ID P 008, LS |
| GSM464257 |
Psoriasis skin, ID P 009, NL |
| GSM464258 |
Psoriasis skin, ID P 010, LS |
|
| Relations |
| BioProject |
PRJNA121567 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE18686_RAW.tar |
6.2 Mb |
(http)(custom) |
TAR |
| GSE18686_nonnormalized.txt.gz |
17.9 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
|
|
|
|
 |
Less...
More...