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| Status |
Public on Feb 28, 2022 |
| Title |
Gene expression data from the syngeneic mouse endometriosis model |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Retrograde menstruation is considered a major reason for the development of endometriosis. The syngeneic transplantation mouse model is an endometriosis animal model that is considered to mimic retrograde menstruation. However, it remains poorly understood which genetic signatures of endometriosis are reflected in this model.
Here, we employed an in vivo syngeneic mouse endometriosis model and identified differentially expressed genes (DEGs) between the ectopic and eutopic tissues using microarray analysis.
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| Overall design |
Total RNA was isolated from the mouse ectopic cystic tissue or uterus using an RNeasy Lipid Tissue Mini Kit (Qiagen Inc., Hilden, Germany) (n = 5 animals per group). Purified RNA was labeled by using the GeneChip WT Plus Reagent Kit (Thermo Fisher Scientific, Inc.), then hybridized to a Clariom S Mouse Array (Thermo Fisher Scientific, Inc.).
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| Contributor(s) |
Iwasaki S, Kaneda K |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Dec 05, 2021 |
| Last update date |
Mar 02, 2022 |
| Contact name |
Shiho Iwasaki |
| E-mail(s) |
s.iwasaki@po.nippon-shinyaku.co.jp
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| Phone |
07024505910
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| Organization name |
Nippon Shinyaku Co., Ltd.
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| Street address |
14, Nishinosho-monguchi-cho, Kisshoin, Minami-ku
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| City |
Kyoto |
| State/province |
Kyoto |
| ZIP/Postal code |
6018550 |
| Country |
Japan |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (15)
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| Relations |
| BioProject |
PRJNA786343 |
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