|
| Status |
Public on Jan 08, 2022 |
| Title |
circZFR promote lung carcinogenesis and oxidative phosphorylation by modulating alternative splicing |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Our study suggested that circZFR was a potential oncogene in lung adenocarcinoma. To investigate the function of circZFR, we performed high-thoughput RNA sequencing (RNA-Seq) assays after the silence of circZFR in A549 cell lines.
|
| |
|
| Overall design |
In human lung adenocarcinoma A549 cells, we downregulated the expression of circZFR utilizing small interference RNA (siRNA) and used scrumble as negative control. Then we used RNA-Seq to reveal the change of mRNA profiles after the silence of circZFR.
|
| |
|
| Contributor(s) |
Ma Z, Chen H, Xu Y, Wang S, Han C, Xia W, Yin R, Xu L |
| Citation(s) |
37461053 |
| Submission date |
Jan 05, 2022 |
| Last update date |
Sep 12, 2023 |
| Contact name |
Keith Ma |
| E-mail(s) |
626259564@163.com
|
| Phone |
15720809028
|
| Organization name |
Nanjing Medical University
|
| Street address |
No.44 Baiziting Road
|
| City |
Nanjing |
| ZIP/Postal code |
210000 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA794353 |
Less...
More...