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Series GSE193122 Query DataSets for GSE193122
Status Public on Aug 23, 2022
Title SARS-CoV-2 Variant Delta Potently Suppresses Innate Immune Response and Evades Interferon-Activated Antiviral Responses in Human Colon Epithelial Cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Here we report differential regulation of innate immune response by SARS-CoV-2 variants and immune antagonism by Alpha and Delta variant.
 
Overall design Caco-2 cells were infected with four different variant isolates of SARS-CoV-2 for 24-, 48- and 72 hrs and the differential host gene expression was performed by RNA deep sequencing.
 
Contributor(s) Tandel D, Sah V, Singh NK, Poojitha S, Sowpati DT, Harshan KH
Citation(s) 36073824
Submission date Jan 05, 2022
Last update date Oct 17, 2022
Contact name Nitesh Kumar Singh
E-mail(s) nitesh@ccmb.res.in
Organization name Center for Cellular and Molecular Biology
Department Bioinformatics
Street address Habsiguda
City Hyderabad
State/province Telangana
ZIP/Postal code 500007
Country India
 
Platforms (1)
GPL23227 BGISEQ-500 (Homo sapiens)
Samples (45)
GSM5773682 Caco2 cells 24h Mock-1
GSM5773683 Caco2 cells 24h Mock-2
GSM5773684 Caco2 cells 24h Mock-3
Relations
BioProject PRJNA794861

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE193122_countMatrix_unstranded_upload.count.txt.gz 7.2 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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