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| Status |
Public on Jan 15, 2022 |
| Title |
Expression data from murine MPS I fibroblasts under flavonoids treatment |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Flavonoids are biological compounds with high potency to modulate molecular processes. The study was designed to estimate genistein, kaempferoland their mixture impact on global gene expression, with special focus on key processes in MPS pathogenesis.
We used microarrays to detail the global program of gene expression underlying flavonoid treatment and identified distinct classes of regulated genes during this process.
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| Overall design |
Murine MPS I fibroblasts were cultivated for 24 hours with 60 and 120 µM genistein, 60 and 120 µM kaempferol and 60 and 120 µM genistein and kaempferol 1:1 mixture.
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| Contributor(s) |
Moskot M, Gabig-Cimińska M |
| Citation(s) |
35162981 |
| Submission date |
Jan 12, 2022 |
| Last update date |
Mar 24, 2022 |
| Contact name |
Marta Magdalena Moskot |
| E-mail(s) |
marta.moskot@ug.edu.pl
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| Phone |
+48 58 523 6045
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| Organization name |
Institute of Biochemistry and Biophysics, Polish Academy of Sciences
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| Lab |
Laboratory of Molecular Biology of Human Skin Diseases
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| Street address |
Kładki 24
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| City |
Gdańsk |
| ZIP/Postal code |
80-822 |
| Country |
Poland |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (16)
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| GSM5814731 |
murine MPS I fibroblast 60 µM genistein, biological rep1 |
| GSM5814732 |
murine MPS I fibroblast 60 µM genistein, biological rep2 |
| GSM5814733 |
murine MPS I fibroblast 120 µM genistein, biological rep1 |
| GSM5814734 |
murine MPS I fibroblast 120 µM genistein, biological rep2 |
| GSM5814735 |
murine MPS I fibroblast 60 µM kaempferol, biological rep1 |
| GSM5814736 |
murine MPS I fibroblast 60 µM kaempferol, biological rep2 |
| GSM5814737 |
murine MPS I fibroblast 120 µM kaempferol, biological rep1 |
| GSM5814738 |
murine MPS I fibroblast 120 µM kaempferol, biological rep2 |
| GSM5814739 |
murine MPS I fibroblast 60 µM genistein and kaempferol 1:1 mixture, biological rep1 |
| GSM5814740 |
murine MPS I fibroblast 60 µM genistein and kaempferol 1:1 mixture, biological rep2 |
| GSM5814741 |
murine MPS I fibroblast 120 µM genistein and kaempferol 1:1 mixture, biological rep1 |
| GSM5814742 |
murine MPS I fibroblast 120 µM genistein and kaempferol 1:1 mixture, biological rep2 |
| GSM5814743 |
murine MPS I fibroblast 0.05% DMSO, biological rep1 |
| GSM5814744 |
murine MPS I fibroblast 0.05% DMSO, biological rep2 |
| GSM5814745 |
murine MPS I fibroblast 0.1% DMSO, biological rep1 |
| GSM5814746 |
murine MPS I fibroblast 0.1% DMSO, biological rep2 |
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| Relations |
| BioProject |
PRJNA796690 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE193583_RAW.tar |
22.1 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| GSE193583_Results_with_annotation_Clariom_S.xlsx |
11.7 Mb |
(ftp)(http) |
XLSX |
| Processed data provided as supplementary file |
| Processed data included within Sample table |
| Processed data are available on Series record |
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