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| Status |
Public on Jun 12, 2023 |
| Title |
Transcriptional comparison of Testicular Adrenal Rest Tumors with fetal and adult tissues |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
By comparing the transcriptome of TART with fetal- and adult- testis and adrenal tissues, this study aimed to unravel the origin of TART. Sixteen TART samples were previously obtained from patients with CAH (n=7) or recurrent Cushing’s Disease (n=1). Adult adrenal (n=11), adult testis (n=10), fetal adrenal (n=13), and fetal testis (n=5) tissues were obtained.
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| Overall design |
Transcriptomic comparisson of Testicular Adrenal Rest Tumors (TART) (n=16) obtained from patients with Congenital Adrenal Hyperplasia (n=7) or recurrent Cushing's Disease (n=1) with adult adrenal (n=11), adult testis (n=10), fetal adrenal (n=13), and fetal testis (n=5) tissues, and Leydig Cell Tumors (n=7).
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| Contributor(s) |
Schröder MA, Sweep FC, van Herwaarden AE, Mitchell RT, Rowan AE, Korbie D, Claahsen - van der Grinten HL, Span PN |
| Citation(s) |
36047744 |
| Submission date |
Feb 14, 2022 |
| Last update date |
Jun 12, 2023 |
| Contact name |
Mariska AM Schröder |
| E-mail(s) |
mariska.schroder@radboudumc.nl
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| Organization name |
Radboud university medical center
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| Department |
Department of Pediatric Endocrinology and Department of Laboratory Medicine
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| Street address |
Geert Grooteplein
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| City |
Nijmegen |
| ZIP/Postal code |
6500HB |
| Country |
Netherlands |
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| Platforms (1) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
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| Samples (62)
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| Relations |
| BioProject |
PRJNA806920 |
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