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| Status |
Public on Oct 04, 2022 |
| Title |
Dual specificity and target gene selection by the MADS domain protein FRUITFULL |
| Organism |
synthetic construct |
| Experiment type |
Other
|
| Summary |
How transcription factors of a single family confer different functional specificities in vivo, is an important question in molecular biology. Even more intriguingly, a single transcription factor can regulate context- or tissue-specific target genes to achieve distinct functions. Here we show, using a variety of genome-wide techniques, that gene regulation and DNA binding site selection by the MADS domain protein FRUITFULL (FUL) is tissue-specific. FUL has a dual role in regulating floral transition and fruit development.
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| Overall design |
SELEX-seq experiments of several Arabidopsis MADS-domain transcription factor dimers.
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| Contributor(s) |
van Mourik H, Bemer M, Muino JM, Angenent G |
| Citation(s) |
36797351 |
| Submission date |
Mar 28, 2022 |
| Last update date |
May 22, 2023 |
| Contact name |
Jose M. Muino |
| E-mail(s) |
jose.muino@hu-berlin.de
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| Organization name |
Humboldt University
|
| Department |
Department of Biology
|
| Street address |
Rhoda-Erdmann-Haus (Haus 22); R 1216 Philippstr. 11-13;
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| City |
Berlin |
| ZIP/Postal code |
10115 |
| Country |
Germany |
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| Platforms (1) |
| GPL15228 |
Illumina HiSeq 2000 (synthetic construct) |
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| Samples (28)
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| Relations |
| BioProject |
PRJNA820961 |
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