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| Status |
Public on May 04, 2023 |
| Title |
A hPSC system for characterizing MUC5B-expressing airway epithelia |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
scRNA-seq of air-liquid interface airway epithelial cultures derived from a human fluorescent reporter hPSC line labeling MUC5B-expressing cells
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| Overall design |
A biallelic MUC5B-tdTomato reporter hPSC line was generated from an individual with progressive fibrotic interstitial lung disease and homozygous for the MUC5B rs35705950 risk allele. Derived airway-ALI cultures were differentiated from this line and sequenced 21 days following air-phase transition.
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| Contributor(s) |
Si S, Wang F, Kotton D |
| Citation missing |
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| Submission date |
May 05, 2022 |
| Last update date |
May 07, 2023 |
| Contact name |
Feiya Wang |
| E-mail(s) |
feiyaw@bu.edu
|
| Organization name |
Center for Regenerative Medicine, Boston University
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| Street address |
670 Albany street, 2nd floor
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| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02118 |
| Country |
USA |
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| Platforms (1) |
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| Samples (1) |
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| Relations |
| BioProject |
PRJNA835444 |
