|
| Status |
Public on Dec 14, 2010 |
| Title |
TAL1 knock down in human erythroid progenitors |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We used microarray profiling in erythroid cells to uncover TAL1 dependent genes in a hematopoietic differentiation context.
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| |
|
| Overall design |
Differentiated ex vivo hematopoietic multipotential progenitors isolated from adult peripheral blood. The knockdown of TAL1 (KD) was induced in pro-erythroblasts (Days 8 and 9 of differentiation) using lentivirus-delivered shRNA. A scramble (scr) shRNA sequence was used as a negative control.
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| |
|
| Contributor(s) |
Brand M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Feb 26, 2010 |
| Last update date |
Jul 26, 2018 |
| Organization |
Ottawa Hospital Research Institute |
| Phone |
(613) 737-8899 -73255
|
| Department |
Cellular and Molecular Medicine
|
| Lab |
Ottawa Bioinformatics Core Facility
|
| Street address |
501 Smyth Rd.
|
| City |
Ottawa |
| State/province |
ON |
| ZIP/Postal code |
K1H 8L6 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (8)
|
| GSM516235 |
human erythroid progenitors TAL1 knock down replicate 1 |
| GSM516236 |
human erythroid progenitors scramble replicate 1 |
| GSM516237 |
human erythroid progenitors TAL1 knock down replicate 2 |
| GSM516238 |
human erythroid progenitors scramble replicate 2 |
| GSM516239 |
human erythroid progenitors TAL1 knock down replicate 3 |
| GSM516240 |
human erythroid progenitors scramble replicate 3 |
| GSM516241 |
human erythroid progenitors TAL1 knock down replicate 4 |
| GSM516242 |
human erythroid progenitors scramble replicate 4 |
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| This SubSeries is part of SuperSeries: |
|
| Relations |
| BioProject |
PRJNA129859 |
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