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| Status |
Public on Mar 03, 2012 |
| Title |
Liver transcriptome profiling of liver specific miR-122 knockout and control male mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Liver transcriptome profiling of liver specific miR-122 knockout (miR-122loxP/loxP Alb-Cre) and control (miR-122loxP/loxP) male mice. Expression profile of several hundred mRNAs that include miR-122 targets were altered in miR-122 KO livers.
Loss of miR-122 in the germ line resulted in significant changes in hepatic gene expression profile. Among the upregulated genes many are direct targets of miR-122
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| Overall design |
GSM517838-GSM517847: Liver transcriptome profiling of liver specific miR-122 knockout and control male mice. Total liver RNA from 8 week old five control and five liver-specific miR-122 knock out male mice (C57/BL6J background)
GSM791601-GSM791604: Liver transcriptome profiling of germ-line miR-122 knockout and control male mice. Liver RNA from 5 week old control (floxed) and miR-122KO mice were analyzed by mouse whole transcriptome profiling.
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| Contributor(s) |
Ghoshal K, Kutay H, Motiwala T, Warner S, Wise T, Yu L |
| Citation(s) |
22820288 |
| Submission date |
Mar 03, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
kalpana ghoshal |
| E-mail(s) |
kalpana.ghoshal@osumc.edu
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| Phone |
614-292-8865
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| Fax |
614-688-5600
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| Organization name |
The Ohio State University
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| Department |
Molecular and Cellular Biochemistry
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| Street address |
420 W. 12th Avenue
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| City |
Columbus |
| State/province |
OH |
| ZIP/Postal code |
43210 |
| Country |
USA |
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| Platforms (2) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA124787 |
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