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Status |
Public on Dec 01, 2011 |
Title |
Methylation data from Down syndrome and non-Down syndrome pediatric acute lymphoblastic leukemia cases and controls |
Organism |
Homo sapiens |
Experiment type |
Methylation profiling by array
|
Summary |
Methylation profiling can reveal patterns of hypermethlation and hypomethylation associated with distinct biologic subtypes of acute lymphoblastic leukemia (ALL). We performed methylation profiling of Down syndrome ALL cases and controls to identify unique biologic features of this ALL subgroup.
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Overall design |
Ficoll-enriched, cryopreserved bone marrow aspirate samples were obtained from patients with B-precursor ALL at diagnosis and in remission
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Contributor(s) |
Rabin KR, Leung E |
Citation(s) |
21647151 |
Submission date |
Mar 13, 2010 |
Last update date |
Jan 02, 2015 |
Contact name |
Hon-chiu Eastwood Leung |
E-mail(s) |
exleung@txccc.org
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Phone |
832-824-4373
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Fax |
832-825-4038
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URL |
http://www.txccc.org/content.cfm?content_id=1405
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Organization name |
Baylor College of Medicine
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Department |
Pediatrics
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Lab |
Genomics and Proteomics Core Laboratory
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Street address |
1102 Bates Street Room C1030.09
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City |
Houston |
State/province |
TX |
ZIP/Postal code |
77030 |
Country |
USA |
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Platforms (1) |
GPL8490 |
Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2) |
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Samples (23)
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This SubSeries is part of SuperSeries: |
GSE21094 |
Genomic profiling in Down syndrome pediatric acute lymphoblastic leukemia |
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Relations |
BioProject |
PRJNA129633 |