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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Mar 31, 2023 |
| Title |
STIL/AURKA axis promotes cell proliferation by influencing primary cilia formation in bladder cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Our research showed that primary cilia was reduced in human bladder cancer (BLCA) cells, and PC deficiency promote cell proliferation. However, the concrete mechanisms remain unknown. SCL/TAL1 interrupting locus (STIL), a PC-related protein, was screened in our previous study and could influence the cell cycle by regulating PC in tumor cells. To elucidate the function of STIL for PC to explore the underlying mechanism of PC in BLCA, we establisded siNC and siSTIL EJ cells.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for EJ-siNC and EJ-siSTIL cells.
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| Contributor(s) |
Li J, Qi Y, Zhang Z, Du E |
| Citation(s) |
37101292 |
| Submission date |
Aug 18, 2022 |
| Last update date |
May 12, 2023 |
| Contact name |
Jingxian Li |
| E-mail(s) |
lijingxian@tmu.edu.cn
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| Organization name |
Tianjin institute of urology
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| Street address |
Pingjiang Road 23#, Hexi District, Tianjin
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| City |
Tianjin |
| ZIP/Postal code |
300211 |
| Country |
China |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA870915 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE211563_RAW.tar |
1.3 Mb |
(http)(custom) |
TAR (of TXT) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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