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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jul 06, 2010 |
| Title |
Identification of genes controlled by LMX1B in the developing limb, embryonic day (E) 13.5 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
A control vs. genetic knockout experiment aimed at determining what RNAs are upregulated or downregulated in E13.5 mouse limb tissue lacking the Lmx1b gene. Because LMX1B is required for dorsal-ventral patterning of the limb, this screen gives insight into what putative downstream targets of Lmx1b contribute to dorsal-ventral patterning.
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| Overall design |
The forelimb or hindlimb of wild-type controls or Lmx1b loss-of-function mutants was used for RNA extraction. Each array was hybridized with cDNAs of an individual limb.
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| Contributor(s) |
Gu WX, Kania A |
| Citation(s) |
20589901 |
| Submission date |
Apr 21, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Xiao Wei Wendy Gu |
| E-mail(s) |
xiaoweiwendy.gu@ircm.qc.ca
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| Phone |
5149875588
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| Organization name |
IRCM
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| Department |
Neural Circuit Development Laboratory
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| Lab |
Dr. Artur Kania
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| Street address |
110, avenue des Pins Ouest
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| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H2W 1R7 |
| Country |
Canada |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (20)
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| GSM536047 |
Wild-type limb at E13.5, biological rep1 |
| GSM536048 |
Wild-type limb at E13.5, biological rep2 |
| GSM536049 |
Wild-type limb at E13.5, biological rep3 |
| GSM536050 |
Wild-type limb at E13.5, biological rep4 |
| GSM536051 |
Wild-type limb at E13.5, biological rep5 |
| GSM536052 |
Wild-type limb at E13.5, biological rep6 |
| GSM536053 |
Wild-type limb at E13.5, biological rep7 |
| GSM536054 |
Wild-type limb at E13.5, biological rep8 |
| GSM536055 |
Wild-type limb at E13.5, biological rep9 |
| GSM536056 |
Wild-type limb at E13.5, biological rep10 |
| GSM536057 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep1 |
| GSM536058 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep2 |
| GSM536059 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep3 |
| GSM536060 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep4 |
| GSM536061 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep5 |
| GSM536062 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep6 |
| GSM536063 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep7 |
| GSM536064 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep8 |
| GSM536065 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep9 |
| GSM536066 |
Lmx1b loss-of-function mutant limb at E13.5, biological rep10 |
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| Relations |
| BioProject |
PRJNA126333 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE21446_RAW.tar |
74.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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