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| Status |
Public on May 17, 2023 |
| Title |
Expression data from RAW264.7 cells infected with wild-type vs srfJ mutant Salmonella enterica serovar Typhimurium |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
SrfJ is an effector of the type III secretion systems of the Gram-negative intracellular pathogen Salmonella enterica serovar Typhimurium.
To study the effects of this effector on global gene expression in host cells, we have infected murine RAW264.7 macrophages with two strains of Salmonella enterica serovar Typhimurium. The comparison between cells infected with the wild-type strain and cells infected with a srfJ mutant revealed a number of genes that are differentially expressed when SrfJ is present.
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| Overall design |
Two conditions. Each condition replicated three times. Condition 1: RAW264.7 macrophages infected with wild-type strain 14028 of Salmonella enterica serovar Typhimurium. Condition 2: RAW264.7 macrophages infected with srfJ null mutant strain of Salmonella enterica serovar Typhimurium.
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| Contributor(s) |
Bernal-Bayard J, Aguilera-Herce J, Balbontín R, Ramos-Morales F |
| Citation(s) |
37176110 |
| Submission date |
Oct 07, 2022 |
| Last update date |
May 19, 2023 |
| Contact name |
Francisco Ramos-Morales |
| E-mail(s) |
framos@us.es
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| Organization name |
Universidad de Sevilla
|
| Department |
Genética
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| Street address |
Avda Reina Mercedes, 6
|
| City |
Sevilla |
| State/province |
Sevilla |
| ZIP/Postal code |
41012 |
| Country |
Spain |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA888127 |
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