|
Status |
Public on Aug 31, 2010 |
Title |
Germ-free and anti-biotic treated rats |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by array
|
Summary |
The objective of the study was identify hepatic genes with expression by deprivation of gut flora. Two models were used: model 1 (study 1443KR) examined germ-free Sprague Dawley and model 2 (1512KR) examined antibiotic treated Han Wistar rats.
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|
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Overall design |
Germ-free vs. non-germ-free, antibiotic treated vs. untreated
|
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Contributor(s) |
Sidaway JE |
Citation(s) |
20837534 |
Submission date |
May 20, 2010 |
Last update date |
Jul 31, 2017 |
Contact name |
James Sidaway |
E-mail(s) |
james.sidaway@astrazeneca.com
|
Organization name |
AstraZeneca
|
Department |
Safety Assessment
|
Lab |
Molecular Toxicology
|
Street address |
Mereside, Alderely Park
|
City |
Macclesfield |
ZIP/Postal code |
SK10 9TG |
Country |
United Kingdom |
|
|
Platforms (1) |
GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
|
Samples (12)
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Relations |
BioProject |
PRJNA126879 |