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| Status |
Public on Feb 16, 2011 |
| Title |
Early and Late gene expression responses to Salmonella infection in the mouse intestine |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
We used microarrays to detail the global programme of gene expression of the mouse colon responses to Salmonella (SL1344 and SB1117) infection at the early phase (8 hours) and the late phase (4 days).
We specifically examined the the differentillay gene expression profiles in mouse colon when it responded to pathogenic Salmonella stain SL1344 (with AvrA expression) or SB1117 (without AvrA expression).
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| Overall design |
Mice were infected with 1x107 CFU of samonella stains, SL1344 and SB1117 respectively (100µl suspension in HBSS) or treated with sterile HBSS (control) by oral gavage as previously described. At 8 hours and 4 days after infection, mice were sacrificed and RNA tissue samples from the intestinal tracts were removed for analysis.
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| Contributor(s) |
Liu X, Sun J, Lu R, Wu S, Xia Y |
| Citation(s) |
21172007 |
| Submission date |
Jun 08, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Jun Sun |
| Organization name |
university of rochester
|
| Street address |
575 Elmwood Ave
|
| City |
Rochester |
| State/province |
MN |
| ZIP/Postal code |
14620 |
| Country |
USA |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (18)
|
| GSM552943 |
Colon with SL1344 infection at 8hr biological rep1 |
| GSM552944 |
Colon with SL1344 infection at 8hr biological rep2 |
| GSM552945 |
Colon with SL1344 infection at 8hr biological rep3 |
| GSM552946 |
Colon with SB1117 infection at 8hr biological rep1 |
| GSM552947 |
Colon with SB1117 infection at 8hr biological rep2 |
| GSM552948 |
Colon with SB1117 infection at 8hr biological rep3 |
| GSM552949 |
Control at 4day biological rep1 |
| GSM552950 |
Control at 4day biological rep2 |
| GSM552951 |
Control at 4day biological rep3 |
| GSM552952 |
Colon with SL1344 infection at 4day biological rep1 |
| GSM552953 |
Colon with SL1344 infection at 4day biological rep2 |
| GSM552954 |
Colon with SL1344 infection at 4day biological rep3 |
| GSM552955 |
Colon with SB1117 infection at 4day biological rep1 |
| GSM552956 |
Colon with SB1117 infection at 4day biological rep2 |
| GSM552957 |
Colon with SB1117 infection at 4day biological rep3 |
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| Relations |
| BioProject |
PRJNA128769 |
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