|
| Status |
Public on Jun 07, 2011 |
| Title |
Expression data from ileum of inducible intestine-specific GATA6 knockout mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
GATA6 is a transcription factor involved in the differentiation of intestinal epithelial cells into differentiated absorptive epithelial cells.
GATA6 is expressed in all segments of the small intestine. We examined the impact of deleting GATA6 from intestinal epithelial cells of the adult ileum
|
| |
|
| Overall design |
6-8 week old Villin-CreERT2 mice or Villin-CreERT2 mice crossed to GATA6 flox/flox mice were treated with a single injection of tamoxifen. (100 mg/ml) for 5 consecutive days. 28 days later the ileum was dissected and RNA prepared from the whole ileal segment using the RNAeasy method with DNAse treatment. Three individual mice were examined in each of the control and GATA6 KO groups.
|
| |
|
| Contributor(s) |
Beuling E, Baffour-Awauh NA, Stapleton KA, Noah TK, Shroyer NF, Duncan SA, Fleet JC, Krasinski SD |
| Citation(s) |
21262227 |
| Submission date |
Jun 17, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
James C Fleet |
| E-mail(s) |
james.fleet@austin.texas.edu
|
| Organization name |
University of Texas at Austin
|
| Department |
Nutritional Sciences
|
| Street address |
1400 Barbara Jordan Blvd
|
| City |
Austin |
| State/province |
TX |
| ZIP/Postal code |
78732 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA128561 |
Less...
More...