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| Status |
Public on Nov 14, 2023 |
| Title |
ChIP-seq following CRISPRi perturbations to MYC enhancers in K562 cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We previous identified enhancers that regulate MYC expression in K562 cells (Fulco et al. Science 2016). Here, we perturbed MYC enhancers with individual CRISPRi gRNAs and performed ChIP-seq to study the effects on chromatin state.
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| Overall design |
ChIP-seq following CRISPRi perturbations to MYC enhancers in K562 cells
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| Contributor(s) |
Engreitz JM, Perez EM, Fulco CP, Anyoha R |
| Citation(s) |
38014075 |
| Submission date |
Feb 12, 2023 |
| Last update date |
Dec 14, 2023 |
| Contact name |
Jesse Engreitz |
| Organization name |
Broad Institute
|
| Street address |
415 Main Street
|
| City |
Cambridge |
| State/province |
MA |
| ZIP/Postal code |
02142 |
| Country |
USA |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (54)
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| Relations |
| BioProject |
PRJNA934120 |
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