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| Status |
Public on Jun 30, 2023 |
| Title |
Pasteurization of human milk affects the miRNA EVs cargo decreasing its immune modulatory activity |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
We hypothesize that the collection, pooling, pasteurization, and freezing storage of the DHM exerts chemical and biological changes besides depleting the beneficial microbes and inactivating bioactive components in MOM. In this report, we evaluated the effect of the pasteurization process of DHM on the miRNA content of MOM EVs and their impact on innate immune response in human cell lines.
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| Overall design |
RNA was extracted from human milk exosomes
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| |
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| Contributor(s) |
Torrez Lamberti MF, Parker LA, Gonzalez CF, Lorca GL |
| Citation(s) |
37344543 |
| BioProject |
PRJNA930463 |
| Submission date |
Feb 22, 2023 |
| Last update date |
Sep 08, 2023 |
| Contact name |
Monica F Torrez Lamberti |
| E-mail(s) |
m.torrezlamberti@ufl.edu
|
| Phone |
3527455116
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| Organization name |
University of Florida
|
| Department |
Microbiology and Cell Science
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| Lab |
Lorca Lab
|
| Street address |
2033 Mowry Rd
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| City |
Gainesville |
| State/province |
FL |
| ZIP/Postal code |
32610 |
| Country |
USA |
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| Platforms (1) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
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| Samples (6)
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