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| Status |
Public on Apr 30, 2024 |
| Title |
The mRNA and lncRNA profiles of verrucoushyperplasia (VH) and verrucouscarcinoma (VC) compared to SCC |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
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| Summary |
Squamous cell carcinoma (SCC) is the most common malignant tumor in the oral cavity, accounting for approximately 90% of all oral cancers. Verrucous carcinoma (VC), a rare low-grade variant of SCC, accounts for 2–12% of all oral malignancies and has a 5-year survival rate of approximately 50%. Although VC is considered a variant of SCC, it can be differentiated from SCC due to its benign histological characteristics. Verrucous hyperplasia (VH) is a disease that is differentiated from VC. However, as both diseases have similar gross and pathological features, differential diagnosis of VH and VC is difficult. We performed RNA sequencing to identify mRNAs and lncRNAs profiles of VH and VC samples.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for VH, VC and SCC
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| Contributor(s) |
Kim J, Kim Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 05, 2023 |
| Last update date |
Apr 30, 2024 |
| Contact name |
JANGHYUN KIM |
| E-mail(s) |
kphe22@gmail.com
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| Organization name |
CNUDH
|
| Department |
Oral pathology
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| Lab |
YKimLab
|
| Street address |
33, YONGBONG-RO, BUK-GU, GWANGJU
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| City |
Gwangju |
| State/province |
Gwangju |
| ZIP/Postal code |
61186 |
| Country |
South Korea |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (21)
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| Relations |
| BioProject |
PRJNA952512 |
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