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Status |
Public on Apr 29, 2024 |
Title |
Senescent stroma mediates immunosuppression and drives breast cancer progression [CAF] |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
To investigate the gene expression profile of different cancer associated fibroblasts (CAF) subpopulations, we harvested tumors and sorted 4 CAF populations from 3 FVB background 10-week-old MMTV-PyMT mice.
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Overall design |
Comparative gene expression profiling analysis of RNA-seq data for 4 different CAF populations in spontanous MMTV-PyMT tumors.
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Contributor(s) |
Ye J, Ren Q, Stewart SA |
Citation missing |
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NIH grant(s) |
Grant ID |
Grant title |
Affiliation |
Name |
R01 AG059244 |
MICROENVIRONMENTAL CONTROLS OF TUMOR DORMANCY |
WASHINGTON UNIVERSITY |
Sheila A Stewart |
R01 CA217208 |
SENESCENT STROMA STIMULATES INFLAMMATION TO PROMOTE TUMORIGENESIS |
WASHINGTON UNIVERSITY |
Sheila A Stewart |
T32 CA113275 |
Molecular Oncology Training Grant |
WASHINGTON UNIVERSITY |
Lee Ratner |
F31 CA271721 |
Understanding how senescent stromal cells contribute to mammary gland tumorigenesis |
WASHINGTON UNIVERSITY |
Jiayu Ye |
P30 CA091842 |
Cancer Center Support Grant |
WASHINGTON UNIVERSITY |
Timothy J Eberlein |
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Submission date |
Apr 10, 2023 |
Last update date |
Apr 29, 2024 |
Contact name |
Sheila Stewart |
E-mail(s) |
sheila.stewart@wustl.edu
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Organization name |
Washington University School of Medicine
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Street address |
660 South Euclid Avenue
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City |
Saint Louis |
ZIP/Postal code |
314-362-7449 |
Country |
USA |
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Platforms (1) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (12)
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This SubSeries is part of SuperSeries: |
GSE229356 |
Senescent stroma mediates immunosuppression and drives breast cancer progression |
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Relations |
BioProject |
PRJNA954044 |