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Series GSE229362 Query DataSets for GSE229362
Status Public on Apr 01, 2024
Title microRNA signature to support clinical-decision making in patients with suspected Obstructive Sleep Apnea
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Plasmatic microRNA sequencing was conducted in specific matched subgroups of subjects (n = 53) with and without OSA using HTG EdgeSeq miRNA WTA Assay technology.
 
Overall design Obstructive sleep apnea (OSA) is a prevalent syndrome associated with significant morbidity and mortality. Recognizing and comprehensively characterizing the diverse pathogenetic pathways are pivotal steps to enhance outcomes. microRNA (miRNA) profiling represents a promising tool for elucidating pathogenetic mechanisms and developing disease-modifying interventions.

Plasma miRNAs were quantified through RNA sequencing (HTG Molecular Diagnostics, Inc, Tucson, AZ, USA) in 53 matched patients with and without OSA (selected using nearest neighbor propensity score matching by age, sex and body mass index (BMI))
 
Contributor(s) de Gonzalo-Calvo D, Belmonte T
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Apr 11, 2023
Last update date Apr 18, 2024
Contact name David de Gonzalo-Calvo
E-mail(s) dgonzalo@irblleida.cat
Phone 973702201
Organization name IRBLleida
Street address Rovira Roure 80
City Lleida
State/province Lleida
ZIP/Postal code 25196
Country Spain
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (53)
GSM7159262 EDTA-K3 plasma anticoagulant tubes [5-OSA01]
GSM7159263 EDTA-K3 plasma anticoagulant tubes [5-OSA02]
GSM7159264 EDTA-K3 plasma anticoagulant tubes [5-OSA03]
Relations
BioProject PRJNA954274

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE229362_GEO_data_HTG_OSA_Processed_TB.txt.gz 186.2 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record
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