 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Apr 09, 2024 |
| Title |
Chemotherapy induces cell plasticity; controlling plasticity increases therapeutic response. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
One of the most serious issues in modern oncology is the ineffectiveness of treatments in destroying tumours, which leads to tumour recurrence and, ultimately, patient death
To investigated this we analyze plasticity of chemotherapy-resistant cells
|
| |
|
| Overall design |
Gene expression profiling analysis of RNA-seq data for HeLa control cells versus Hela cells treated 24 hours with TRAIL (30 ng/ml), Camptothecin (10 µM) or Doxorrubicin (2 µM).
|
| Web link |
https://www.nature.com/articles/s41392-023-01500-w#Sec1
|
| |
|
| Contributor(s) |
Iborra FJ, Marti C, Calabuig-Navarro V, Papadopoulos P, Mesegue S, Iborra PM, García F, Calatrava A, Martínez-Lorente A, Almazán F, Almazán F, Calabuig J |
| Citation(s) |
37394666 |
| Submission date |
Apr 14, 2023 |
| Last update date |
Apr 10, 2024 |
| Contact name |
Francisco José Iborra |
| E-mail(s) |
fjiborra@ibv.csic.es
|
| Organization name |
Instituto de Biomedicina de Valencia (CSIC)
|
| Street address |
C/ JAIME ROIG, 11
|
| City |
Valencia |
| State/province |
Valencia |
| ZIP/Postal code |
46010 |
| Country |
Spain |
| |
|
| Platforms (1) |
|
| Samples (16)
|
| GSM7177448 |
Hela, Control, rep4 |
| GSM7177449 |
Hela TRAIL (30 ng/ml), 24h, rep1 |
| GSM7177450 |
Hela TRAIL (30 ng/ml), 24h, rep2 |
| GSM7177451 |
Hela TRAIL (30 ng/ml), 24h, rep3 |
| GSM7177452 |
Hela TRAIL (30 ng/ml), 24h, rep4 |
| GSM7177453 |
Hela Camptothecin (10 µM), 24h, rep1 |
| GSM7177454 |
Hela Camptothecin (10 µM), 24h, rep2 |
| GSM7177455 |
Hela Camptothecin (10 µM), 24h, rep3 |
| GSM7177456 |
Hela Camptothecin (10 µM), 24h, rep4 |
| GSM7177457 |
Hela Roxorrubicin (2 µM), 24h, rep1 |
| GSM7177458 |
Hela Roxorrubicin (2 µM), 24h, rep2 |
| GSM7177459 |
Hela Roxorrubicin (2 µM), 24h, rep3 |
| GSM7177460 |
Hela Roxorrubicin (2 µM), 24h, rep4 |
|
| Relations |
| BioProject |
PRJNA955789 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE229761_RAW.tar |
3.0 Mb |
(http)(custom) |
TAR (of TXT) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
|
|
|
|
 |
Less...
More...