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| Status |
Public on Sep 15, 2023 |
| Title |
MAF Amplification licenses Estrogen Receptor α to Drive Breast Cancer Metastasis.[ChIP-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
We performed genome-wide mapping of H3k27ac and H3K4me3 sites in control and MAF-overexpressing MCF7 cells to assess the consequences of estrogen (E2) stimulation and MAF overexpression recruitment to chromatin. To this end, we cultured MCF7 cells in hormone-deprived (HD) medium for 72 h and then E2 or vehicle was added for 1h prior to chromatin immunoprecipitation (ChIP). Samples were generated in triplicate.
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| Overall design |
Examination of H3K27ac and H3K4me3 sites in control and MAF-overexpressing MCF7 cells before and after E2 stimulation.
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| Contributor(s) |
Blasco T, Ballaré C, Blanco E, Caballé A, Gomis R, Di Croce L |
| Citation(s) |
37945904 |
| Submission date |
May 17, 2023 |
| Last update date |
Dec 22, 2023 |
| Contact name |
Adria Caballe |
| E-mail(s) |
adria.caballe@irbbarcelona.org
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| Organization name |
IRB
|
| Department |
biostatistics
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| Street address |
C/ Baldiri Reixac 10
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| City |
Barcelona |
| ZIP/Postal code |
08028 |
| Country |
Spain |
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| Platforms (1) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE232389 |
MAF Amplification licenses Estrogen Receptor α to Drive Breast Cancer Metastasis. |
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| Relations |
| BioProject |
PRJNA973608 |
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