|
| Status |
Public on Aug 12, 2010 |
| Title |
Genome wide transcriptional profiling of c-Cbl deficient hematopoietic stem and progenitor cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Expression of genes that are differentially expressed between c-Cbl control and c-Cbl mutant hematopoietic stem and progenitor cells were identified through this approach. Interestingly, several leukemia associated genes, particularly transcription factors, were differentially expressed between c-Cbl WT and c-Cbl mutant hematopoietic stem and progenitor cells.
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| |
|
| Overall design |
Hematopoietic stem and progenitor cells of c-Cbl control and c-Cbl mutant mice were sorted based on their defined immunophenotype. Gene expression studies were performed using Illumina microarray chips.
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| |
|
| Contributor(s) |
Rathinam C, Flavell RA |
| Citation(s) |
20951944 |
| Submission date |
Aug 11, 2010 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Chozha Vendan Rathinam |
| E-mail(s) |
chozhavendan@yale.edu
|
| Phone |
203-785-5383
|
| Organization name |
Yale School Of Medicine
|
| Department |
Immunobiology
|
| Lab |
Flavell
|
| Street address |
300 Cedar St
|
| City |
New Haven |
| State/province |
CT |
| ZIP/Postal code |
06511 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
|
| Samples (13)
|
|
| Relations |
| BioProject |
PRJNA131797 |
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