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| Status |
Public on Nov 20, 2023 |
| Title |
Effect of METTL3 knockdown on MCF10 breast cancer progression model |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the cellular role of METTL3 in breast cancer progression, we established MCF10-A, MCF10-AT1, and MCF10-CA1H cell lines that had knockdown of METTL3 using CRISPR. We then performed gene expression profiling analysis using data obtained from RNA-seq of the various cell lines.
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| |
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for METTL3 knockdown in MCF10-A, MCF10-AT1, and MCF10-CA1H cell lines.
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| |
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| Contributor(s) |
Dorgham MG, Mansfield KD |
| Citation(s) |
38023205 |
| Submission date |
Jul 11, 2023 |
| Last update date |
Dec 08, 2023 |
| Contact name |
Kyle D. Mansfield |
| E-mail(s) |
mansfieldk@ecu.edu
|
| Organization name |
East Carolina University, Brody School of Medicine
|
| Department |
Biochemistry and Molecular Biology
|
| Street address |
600 Moye Blvd, MS622
|
| City |
Greenville |
| State/province |
NC |
| ZIP/Postal code |
27834 |
| Country |
USA |
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| Platforms (1) |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA993659 |
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