|
| Status |
Public on Mar 14, 2012 |
| Title |
Effect of Valproic Acid on Endothelial Cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Valproic acid (VPA) is a short-chain fatty acid used in the treatment of epilepsy and also considered to be an epigenetic modifier by functioning as a histone deacetylase (HDAC)-inhibitor. The aim of this study was to search for gene altered by VPA in human endothelial cells.
|
| |
|
| Overall design |
Human umbilical vein endothelial cells (HUVEC) from five individuals were cultured in the absence or presence of 4mM VPA for 24h. Cells were cultured in EGM-2 medium and all experiments were performed in passages 1 or 2.
|
| |
|
| Contributor(s) |
Magnusson M, Larsson P, Ulfhammer E, Svensson P, Karlsson L, Jern S |
| Citation(s) |
22363677 |
| Submission date |
Aug 31, 2010 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Per-Arne Svensson |
| E-mail(s) |
per-arne.svensson@medic.gu.se
|
| Phone |
+46 31 3426736
|
| Organization name |
institute of medicine
|
| Department |
Department of molecular and clinical medicine
|
| Lab |
lab 13, w-lab
|
| Street address |
Vitastraket12
|
| City |
Gothenburg |
| ZIP/Postal code |
41345 |
| Country |
Sweden |
| |
|
| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA130543 |
Less...
More...