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| Status |
Public on Aug 24, 2011 |
| Title |
Role and function of STAT5 in BCR-ABL1 driven pre-B cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
In order to investigate the function of STAT5 in ALL, we isolated bone marrow cells from STAT5 fl/fl mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells were transformed either with CRE-GFP or empty vector control (GFP) and subjected to gene expression analysis.
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| |
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| Overall design |
Three days post transduction, total RNA of GFP positive sorted cells was extracted and subjected to gene expression analysis.
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| |
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| Contributor(s) |
Ramezani-Rad P |
| Citation(s) |
21911423, 23852341 |
| Submission date |
Oct 20, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Markus Müschen |
| E-mail(s) |
mmuschen@chla.usc.edu
|
| Phone |
+ 1 323 361 5592
|
| Fax |
+1 323 361 1516
|
| URL |
http://www.lymphocytes.de/
|
| Organization name |
University of Southern California
|
| Department |
Childrens Hospital Los Angeles
|
| Lab |
Müschen Lab
|
| Street address |
4650 Sunset Blvd
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90027 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (6)
|
| GSM610862 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell cre chip1 |
| GSM610863 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell cre chip2 |
| GSM610864 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell cre chip3 |
| GSM610865 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell pMIG chip1 |
| GSM610866 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell pMIG chip2 |
| GSM610867 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell pMIG chip3 |
|
| Relations |
| BioProject |
PRJNA132193 |
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