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| Status |
Public on Dec 06, 2023 |
| Title |
Effect of methionine-chorine-deficient diet (MCD) on whole gene expression in murine liver [mRNA] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
It is known that administration of MCD induces a severe state of hepatic fibrosis in mice.
To attempt to elucidate molecular mechanism of hepatic fibrosis, we performed whole transcriptome analysis by microarray using RNAs prepared from liver of wild-type mice fed with normal diet (ND) or MCD.
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| Overall design |
RNAs were prepared from liver of wild-type male C57BL/6J mice fed with ND or MCD. Single-stranded cDNAs derived from the RNAs were hybridized with a Mouse Gene 2.1 ST Array Strip (ThermoFisher Scientific). The array was scanned by the GeneAtlas system (Affymetrix) to measure the intensities of the microarray spots.
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| Contributor(s) |
Higuchi T |
| Citation(s) |
38556264 |
| Submission date |
Dec 06, 2023 |
| Last update date |
Apr 30, 2024 |
| Contact name |
Shuji Sakamoto |
| E-mail(s) |
sshuji@kochi-u.ac.jp
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| Organization name |
Kochi University
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| Department |
Science Research Center
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| Lab |
Laboratory of Molecular Biology
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| Street address |
Oko-cho, Kohasu
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| City |
Nankoku |
| State/province |
Kochi |
| ZIP/Postal code |
783-8505 |
| Country |
Japan |
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| Platforms (1) |
| GPL17400 |
[MoGene-2_1-st] Affymetrix Mouse Gene 2.1 ST Array [transcript (gene) version] |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE249487 |
Effect of methionine-chorine-deficient diet (MCD) in murine liver |
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| Relations |
| BioProject |
PRJNA1049371 |
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