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| Status |
Public on Mar 25, 2024 |
| Title |
Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy. [RNA-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Differential molecular response involving epigenetic, transcriptomic and proteomic adaptstions of glioblastoma cancer stem-like cells and serum differentiaed cells in response to temozolomide and ionizing radiation
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| Overall design |
Patient derived glioblastoma cancer stem-like cells and 2% FBS differentiated cells exposed to ionizing radiation (4 Gy) and temozolomide with corresponding controls (n=3 technical replicates)
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| |
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| Contributor(s) |
Nuga O, Berezovsky A, Dutta I, Bergman K, Sabedot T, Gurdziel K, Irtenkauf S, Hasselbach L, Meng Y, Mueller C, Petricoin III EF, Brown S, Aras S, Poisson L, Noushmehr H, Ruden D, deCarvalho AC |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Dec 06, 2023 |
| Last update date |
Mar 25, 2024 |
| Contact name |
oluwademilade Nuga |
| E-mail(s) |
demialloneword@gmail.com
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| Organization name |
Wayne State University
|
| Department |
Pharmacology
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| Lab |
deCarvalho/Todi lab
|
| Street address |
540 E canfield
|
| City |
Detroit |
| State/province |
MI |
| ZIP/Postal code |
48239 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (48)
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| This SubSeries is part of SuperSeries: |
| GSE249637 |
Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy. |
|
| Relations |
| BioProject |
PRJNA1049458 |
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