|
| Status |
Public on Jun 29, 2011 |
| Title |
Dendritic cell response to hypoxia and poly I:C |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Investigation whether hypoxic stabilization of HIF-1alpha quantitatively or qualitatively modifies the gene expression pattern induced by poly I:C, a TLR ligand that does not induce normoxic HIF-1alpha stabilization on its own (non-HIF-1alpha-stabilizing TLR ligand).
Keywords: Comparison of single and combined treatment
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| |
|
| Overall design |
Bone marrow derived Dendritic Cells from mice were stimulated under normoxic or hypoxic conditions for 16h with media or poly I:C. Total cellular RNA was harvested, labeled and hybridised to Affymetrix Mouse Gene ST 1.0 GeneChips. Cel files were normalized with RMA.
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| |
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| Contributor(s) |
Lang R, Jantsch J |
| Citation(s) |
21685248 |
| Submission date |
Oct 28, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Roland Lang |
| E-mail(s) |
roland.lang@uk-erlangen.de
|
| Organization name |
University Hospital Erlangen
|
| Street address |
Wasserturmstr. 3-5
|
| City |
Erlangen |
| ZIP/Postal code |
91054 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA131977 |
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