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| Status |
Public on Dec 14, 2013 |
| Title |
Gene Expression Profiles Distinguish Children with Inactive Polyarticular Juvenile Idiopathic Arthritis (JIA) with a Predilection to Flare |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression profiles were obtained from 17 children with rheumatoid factor negative (RF-) polyarticular juvenile idiopathic arthritis (JIA). The disease was inactive in all patients at visit 1. Thee disease remained inactive at visit 2 for 9 patients, while the other 8 patients were experiencing a disease flare at visit 2. The goal of the study was to better understand the underlying molecular biology of flares in JIA
Total RNA was obtained from PBMC at two different times in the course of disease
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| Overall design |
2 samples from each of 17 patients were collected and analyzed different times in the course of the disease
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| Contributor(s) |
Frank MB, Knowlton N, Armstrong N, Osban J, Jiang K, O’Neil KM, Centola M, Chen Y, Chen J, Jarvis JN |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Dec 16, 2010 |
| Last update date |
Feb 18, 2019 |
| Contact name |
Bart Frank |
| E-mail(s) |
frank@omrf.org
|
| Organization name |
OMRF
|
| Street address |
825 NE 13 St
|
| City |
Oklahoma City |
| State/province |
OK |
| ZIP/Postal code |
73103 |
| Country |
USA |
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| Platforms (1) |
| GPL6884 |
Illumina HumanWG-6 v3.0 expression beadchip |
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| Samples (34)
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| Relations |
| BioProject |
PRJNA135193 |
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