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| Status |
Public on Apr 09, 2024 |
| Title |
Exogenous and endogenous serine modulate polarization of tumor-associated macrophages to influence development of nasopharyngeal carcinoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the global gene expression pattern in response to removal of exogenous serine/glycine from the medium, RNA-seq was performed using C666-1 cells cultured in CM or -SG medium for 24 h. The volcano plot exhibited 60 up-regulated and 123 down-regulated genes in C666-1 cells subjected to exogenous serine/glycine deprivation.
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| Overall design |
After C666-1 cells were cultured in complete or serine/glycine deficient medium for 24 h, total RNA was extracted using TRizol reagent and sequenced on the MGISEQ-2000RS platform.
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| Contributor(s) |
Dai D, Ye J, Xiong Y, Chen N |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 07, 2024 |
| Last update date |
Apr 09, 2024 |
| Contact name |
Yishan Xiong |
| E-mail(s) |
XiongYS03@email.ncu.edu.cn
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| Phone |
13970076315
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| Organization name |
南昌大学第一附属医院
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| Street address |
永外正街17号
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| City |
Nanchang |
| State/province |
Jiangxi Province |
| ZIP/Postal code |
330006 |
| Country |
China |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA1097238 |
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