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| Status |
Public on May 10, 2024 |
| Title |
A chromosome region linked to neurodevelopmental disorders acts in distinct neuronal circuits in males and females to control locomotor behavior |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We report a single nuclei RNA-seq of mouse total striatum to identify gene expression changes in males and female between WT and 16p11.2 hemideletion.
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| Overall design |
We performed single nuclei RNA-sequencing from total striatum of 4 groups: WT males (sample 795 and 809), 16p11.2 del/+ males (sample 796 and 807), WT females (sample 798 and 803), and 16p11.2 del/+ females (sample 806 and 811).
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| Contributor(s) |
Kim J, Vanrobaeys Y, Davatolhagh F, Kelvington B, Lynch III JF, Chatterjee S, Ferri SL, Angelakos C, Mills AA, Fuccillo M, Nickl-Jockschat T, Abel T |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 30, 2024 |
| Last update date |
May 10, 2024 |
| Contact name |
Yann Vanrobaeys |
| E-mail(s) |
yann-vanrobaeys@uiowa.edu
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| Phone |
5059139210
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| Organization name |
University of Iowa
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| Department |
Neuroscience and Pharmacology
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| Lab |
Ted Abel
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| Street address |
169 Newton Road
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| City |
Iowa City |
| State/province |
IA |
| ZIP/Postal code |
52242 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA1106401 |
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