NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE268050 Query DataSets for GSE268050
Status Public on May 22, 2024
Title Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample
Platform organisms Equus asinus; Bos taurus; Mammuthus primigenius; Elephas maximus indicus
Sample organisms Homo sapiens; Equus asinus; Bos taurus; Mammuthus primigenius; Elephas maximus indicus
Experiment type Other
Third-party reanalysis
Summary Analyses of ancient DNA typically involve sequencing the surviving short oligonucleotides, and aligning to genome assemblies from related, modern species. Here, we report that skin from a female woolly mammoth (†Mammuthus primigenius) which died 52,000 years ago retained its ancient genome architecture. We use PaleoHi-C to map chromatin contacts and assemble its genome, yielding twenty-eight chromosome-length scaffolds. Chromosome territories, compartments, loops, Barr bodies, and inactive-X chromosome (Xi) superdomains persist. The active and inactive genome compartments in mammoth skin more closely resemble Asian elephant skin than other elephant tissues. Our analyses uncover new biology. Differences in compartmentalization reveal genes whose transcription was potentially altered in mammoths vs. elephants. Mammoth Xi has a tetradic architecture, not bipartite like human and mouse. We hypothesize that, shortly after this mammoth’s death, the sample spontaneously freeze-dried in the Siberian cold, leading to a glass transition that preserved subfossils of ancient chromosomes at nanometer scale.
 
Overall design We use PaleoHi-C on a skin sample from a 52,000 woolly mammoth to assemble its genome using a reference assited 3D genome assembly method. We show how the method works by assembling a donkey genome, both de novo and using reference-assisted 3D genome assembly. We also assemble genomes of Asian and African elephants. We analyze and compare contact data for the woolly mammoth and the Asian and African elephants. We generate data for multiple Asian elephant tissues and show that the mammoth PaleoHi-C data contains cell-specific information. We map loops. We compare compartmentalization patterns to reveal genes whose transcription was potentially altered in mammoths vs. elephants. We use PaleoHi-C to infer 3D structures of woolly mammoth chromosomes. We perform a series of proof-of-principle experiments using beef to show that dehydration is beneficial for preservation of 3D genome architecture, even at elevated temperatures. The processed files also include reanalysis of GSM1551550-GSM1551578 (Rao, Huntley et al, 2014; Harris, Gu et al., 2023) and ENCFF531FEY (https://www.encodeproject.org/files/ENCFF531FEY).
 
Contributor(s) Dudchenko O, Sandoval-Velasco M, Rodríguez JA, Pérez Estrada C, Marti-Renom MA, Gilbert MT, Aiden EL
Citation missing Has this study been published? Please login to update or notify GEO.
BioProject PRJNA512907
Submission date May 21, 2024
Last update date Jun 11, 2024
Contact name Olga Dudchenko
E-mail(s) Olga.Dudchenko@bcm.edu
Organization name Baylor College of Medicine
Street address 1 Baylor Plaza
City Houston
State/province TX
ZIP/Postal code 77030
Country USA
 
Platforms (10)
GPL27907 NextSeq 550 (Bos taurus)
GPL30098 Illumina HiSeq 2000 (Equus asinus)
GPL34501 DNBSEQ-G400 (Mammuthus primigenius)
Samples (128)
GSM8284993 PaleoHi-C of Mammuthus primigenius DNA Zoo Sample6310, PeloHi-C lib id: 505
GSM8284994 PaleoHi-C of Mammuthus primigenius DNA Zoo Sample6310, PeloHi-C lib id: 506
GSM8284995 PaleoHi-C of Mammuthus primigenius DNA Zoo Sample6310, PeloHi-C lib id: 511
Relations
Reanalysis of GSM1551550
Reanalysis of GSM1551551
Reanalysis of GSM1551552
Reanalysis of GSM1551553
Reanalysis of GSM1551554
Reanalysis of GSM1551555
Reanalysis of GSM1551556
Reanalysis of GSM1551557
Reanalysis of GSM1551558
Reanalysis of GSM1551559
Reanalysis of GSM1551560
Reanalysis of GSM1551561
Reanalysis of GSM1551562
Reanalysis of GSM1551563
Reanalysis of GSM1551564
Reanalysis of GSM1551565
Reanalysis of GSM1551566
Reanalysis of GSM1551567
Reanalysis of GSM1551568
Reanalysis of GSM1551569
Reanalysis of GSM1551570
Reanalysis of GSM1551571
Reanalysis of GSM1551572
Reanalysis of GSM1551573
Reanalysis of GSM1551574
Reanalysis of GSM1551575
Reanalysis of GSM1551576
Reanalysis of GSM1551577
Reanalysis of GSM1551578

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE268050_ASM1433276v1.hic 2.9 Gb (ftp)(http) HIC
GSE268050_ASM1433276v1.rawchrom.hic 2.9 Gb (ftp)(http) HIC
GSE268050_ASM1433276v1_HiC.fasta.gz 948.4 Mb (ftp)(http) FASTA
GSE268050_ASM303372v1.hic 1.8 Gb (ftp)(http) HIC
GSE268050_ASM303372v1.rawchrom.hic 1.8 Gb (ftp)(http) HIC
GSE268050_ASM303372v1_HiC.assembly.txt.gz 87.7 Kb (ftp)(http) TXT
GSE268050_ASM303372v1_HiC.fasta.gz 723.9 Mb (ftp)(http) FASTA
GSE268050_EM_brain_Loxafr3.0_HiC.hic 311.7 Mb (ftp)(http) HIC
GSE268050_EM_brain_Loxafr3.0_HiC_30.hic 275.1 Mb (ftp)(http) HIC
GSE268050_EM_brain_MamPri_ASM1433276v1_assisted_HiC.hic 316.1 Mb (ftp)(http) HIC
GSE268050_EM_brain_MamPri_ASM1433276v1_assisted_HiC_30.hic 281.1 Mb (ftp)(http) HIC
GSE268050_EM_brain_MamPri_Loxafr3.0_assisted_HiC.hic 310.4 Mb (ftp)(http) HIC
GSE268050_EM_brain_MamPri_Loxafr3.0_assisted_HiC_30.hic 277.8 Mb (ftp)(http) HIC
GSE268050_EM_derm_CRUSH_Loxafr3.0_HiC.bedgraph.gz 527.4 Kb (ftp)(http) BEDGRAPH
GSE268050_EM_liver_Loxafr3.0_HiC.hic 304.4 Mb (ftp)(http) HIC
GSE268050_EM_liver_Loxafr3.0_HiC_30.hic 266.8 Mb (ftp)(http) HIC
GSE268050_EM_liver_MamPri_ASM1433276v1_assisted_HiC.hic 308.9 Mb (ftp)(http) HIC
GSE268050_EM_liver_MamPri_ASM1433276v1_assisted_HiC_30.hic 273.0 Mb (ftp)(http) HIC
GSE268050_EM_liver_MamPri_Loxafr3.0_assisted_HiC.hic 303.0 Mb (ftp)(http) HIC
GSE268050_EM_liver_MamPri_Loxafr3.0_assisted_HiC_30.hic 269.5 Mb (ftp)(http) HIC
GSE268050_EM_ovary_Loxafr3.0_HiC.hic 186.4 Mb (ftp)(http) HIC
GSE268050_EM_ovary_Loxafr3.0_HiC_30.hic 165.1 Mb (ftp)(http) HIC
GSE268050_EM_ovary_MamPri_ASM1433276v1_assisted_HiC.hic 188.6 Mb (ftp)(http) HIC
GSE268050_EM_ovary_MamPri_ASM1433276v1_assisted_HiC_30.hic 168.4 Mb (ftp)(http) HIC
GSE268050_EM_ovary_MamPri_Loxafr3.0_assisted_HiC.hic 185.5 Mb (ftp)(http) HIC
GSE268050_EM_ovary_MamPri_Loxafr3.0_assisted_HiC_30.hic 166.5 Mb (ftp)(http) HIC
GSE268050_EM_pbmc_Loxafr3.0_HiC.hic 816.6 Mb (ftp)(http) HIC
GSE268050_EM_pbmc_Loxafr3.0_HiC_30.hic 734.8 Mb (ftp)(http) HIC
GSE268050_EM_pbmc_MamPri_ASM1433276v1_assisted_HiC.hic 832.2 Mb (ftp)(http) HIC
GSE268050_EM_pbmc_MamPri_ASM1433276v1_assisted_HiC_30.hic 753.8 Mb (ftp)(http) HIC
GSE268050_EM_pbmc_MamPri_Loxafr3.0_assisted_HiC.hic 811.9 Mb (ftp)(http) HIC
GSE268050_EM_pbmc_MamPri_Loxafr3.0_assisted_HiC_30.hic 740.3 Mb (ftp)(http) HIC
GSE268050_EM_skin_CRUSH_Loxafr3.0_HiC.bedgraph.gz 526.8 Kb (ftp)(http) BEDGRAPH
GSE268050_EM_skin_Loxafr3.0_HiC.hic 654.5 Mb (ftp)(http) HIC
GSE268050_EM_skin_Loxafr3.0_HiC_30.hic 570.3 Mb (ftp)(http) HIC
GSE268050_EM_skin_MamPri_ASM1433276v1_assisted_HiC.hic 668.8 Mb (ftp)(http) HIC
GSE268050_EM_skin_MamPri_ASM1433276v1_assisted_HiC_30.hic 588.9 Mb (ftp)(http) HIC
GSE268050_EM_skin_MamPri_Loxafr3.0_assisted_HiC.hic 653.2 Mb (ftp)(http) HIC
GSE268050_EM_skin_MamPri_Loxafr3.0_assisted_HiC_30.hic 577.7 Mb (ftp)(http) HIC
GSE268050_EM_skin_derm_Loxafr3.0_HiC.hic 203.3 Mb (ftp)(http) HIC
GSE268050_EM_skin_derm_Loxafr3.0_HiC_30.hic 178.9 Mb (ftp)(http) HIC
GSE268050_EM_skin_sub_Loxafr3.0_HiC.hic 107.2 Mb (ftp)(http) HIC
GSE268050_EM_skin_sub_Loxafr3.0_HiC_30.hic 97.9 Mb (ftp)(http) HIC
GSE268050_EquAsi_EquCab2.0_assisted.hic 1.8 Gb (ftp)(http) HIC
GSE268050_EquAsi_EquCab2.0_assisted.rawchrom.hic 1.8 Gb (ftp)(http) HIC
GSE268050_EquAsi_EquCab2.0_assisted_HiC.fasta.gz 692.8 Mb (ftp)(http) FASTA
GSE268050_HIC1381_ASM1433276v1_HiC.hic 139.3 Mb (ftp)(http) HIC
GSE268050_HIC1381_ASM1433276v1_HiC_30.hic 130.6 Mb (ftp)(http) HIC
GSE268050_HIC1381u_ASM1433276v1_HiC.hic 1.2 Gb (ftp)(http) HIC
GSE268050_HIC1381u_ASM1433276v1_HiC_30.hic 1.0 Gb (ftp)(http) HIC
GSE268050_HIC1382_ASM1433276v1_HiC.hic 833.3 Mb (ftp)(http) HIC
GSE268050_HIC1382_ASM1433276v1_HiC_30.hic 762.8 Mb (ftp)(http) HIC
GSE268050_HIC1382u_ASM1433276v1_HiC.hic 2.2 Gb (ftp)(http) HIC
GSE268050_HIC1382u_ASM1433276v1_HiC_30.hic 2.0 Gb (ftp)(http) HIC
GSE268050_HIC16743+HIC16744.hic 92.9 Mb (ftp)(http) HIC
GSE268050_HIC16743+HIC16744_30.hic 84.7 Mb (ftp)(http) HIC
GSE268050_HIC16916.hic 551.4 Mb (ftp)(http) HIC
GSE268050_HIC16916_30.hic 493.0 Mb (ftp)(http) HIC
GSE268050_HIC16917.hic 526.8 Mb (ftp)(http) HIC
GSE268050_HIC16917_30.hic 471.3 Mb (ftp)(http) HIC
GSE268050_HIC16954+HIC16956.hic 153.8 Mb (ftp)(http) HIC
GSE268050_HIC16954+HIC16956_30.hic 137.5 Mb (ftp)(http) HIC
GSE268050_HIC16963+HIC16964+HIC16982.hic 128.7 Mb (ftp)(http) HIC
GSE268050_HIC16963+HIC16964+HIC16982_30.hic 115.5 Mb (ftp)(http) HIC
GSE268050_HIC16969+HIC16970+HIC16981.hic 119.2 Mb (ftp)(http) HIC
GSE268050_HIC16969+HIC16970+HIC16981_30.hic 106.9 Mb (ftp)(http) HIC
GSE268050_HIC16971+HIC16972+HIC16983.hic 79.2 Mb (ftp)(http) HIC
GSE268050_HIC16971+HIC16972+HIC16983_30.hic 72.3 Mb (ftp)(http) HIC
GSE268050_HIC16973.hic 159.3 Mb (ftp)(http) HIC
GSE268050_HIC16973_30.hic 149.1 Mb (ftp)(http) HIC
GSE268050_HIC16974.hic 159.4 Mb (ftp)(http) HIC
GSE268050_HIC16974_30.hic 149.3 Mb (ftp)(http) HIC
GSE268050_HIC16975.hic 170.7 Mb (ftp)(http) HIC
GSE268050_HIC16975_30.hic 159.3 Mb (ftp)(http) HIC
GSE268050_HIC16976.hic 161.9 Mb (ftp)(http) HIC
GSE268050_HIC16976_30.hic 151.7 Mb (ftp)(http) HIC
GSE268050_HIC16977.hic 149.7 Mb (ftp)(http) HIC
GSE268050_HIC16977_30.hic 140.6 Mb (ftp)(http) HIC
GSE268050_HIC16984.hic 65.4 Mb (ftp)(http) HIC
GSE268050_HIC16984_30.hic 65.3 Mb (ftp)(http) HIC
GSE268050_HIC16986.hic 167.7 Mb (ftp)(http) HIC
GSE268050_HIC16986_30.hic 156.9 Mb (ftp)(http) HIC
GSE268050_HIC16987.hic 172.1 Mb (ftp)(http) HIC
GSE268050_HIC16987_30.hic 160.9 Mb (ftp)(http) HIC
GSE268050_HIC17023.hic 261.4 Mb (ftp)(http) HIC
GSE268050_HIC17023_30.hic 237.9 Mb (ftp)(http) HIC
GSE268050_HIC17027.hic 274.5 Mb (ftp)(http) HIC
GSE268050_HIC17027_30.hic 250.0 Mb (ftp)(http) HIC
GSE268050_HIC17029.hic 287.9 Mb (ftp)(http) HIC
GSE268050_HIC17029_30.hic 262.9 Mb (ftp)(http) HIC
GSE268050_HIC17030.hic 151.5 Mb (ftp)(http) HIC
GSE268050_HIC17030_30.hic 142.5 Mb (ftp)(http) HIC
GSE268050_HIC17031.hic 152.1 Mb (ftp)(http) HIC
GSE268050_HIC17031_30.hic 142.9 Mb (ftp)(http) HIC
GSE268050_HIC17032.hic 146.1 Mb (ftp)(http) HIC
GSE268050_HIC17032_30.hic 137.8 Mb (ftp)(http) HIC
GSE268050_HIC17033.hic 145.7 Mb (ftp)(http) HIC
GSE268050_HIC17033_30.hic 137.4 Mb (ftp)(http) HIC
GSE268050_HIC17034.hic 151.5 Mb (ftp)(http) HIC
GSE268050_HIC17034_30.hic 142.6 Mb (ftp)(http) HIC
GSE268050_HIC17035.hic 163.0 Mb (ftp)(http) HIC
GSE268050_HIC17035_30.hic 153.6 Mb (ftp)(http) HIC
GSE268050_HIC17036.hic 159.3 Mb (ftp)(http) HIC
GSE268050_HIC17036_30.hic 150.2 Mb (ftp)(http) HIC
GSE268050_HIC17037.hic 127.0 Mb (ftp)(http) HIC
GSE268050_HIC17037_30.hic 121.5 Mb (ftp)(http) HIC
GSE268050_HIC17038.hic 153.8 Mb (ftp)(http) HIC
GSE268050_HIC17038_30.hic 145.4 Mb (ftp)(http) HIC
GSE268050_HIC17039.hic 155.8 Mb (ftp)(http) HIC
GSE268050_HIC17039_30.hic 147.3 Mb (ftp)(http) HIC
GSE268050_HIC17040.hic 136.4 Mb (ftp)(http) HIC
GSE268050_HIC17040_30.hic 129.8 Mb (ftp)(http) HIC
GSE268050_HIC17041.hic 101.4 Mb (ftp)(http) HIC
GSE268050_HIC17041_30.hic 98.0 Mb (ftp)(http) HIC
GSE268050_HIC17042.hic 155.0 Mb (ftp)(http) HIC
GSE268050_HIC17042_30.hic 146.6 Mb (ftp)(http) HIC
GSE268050_HIC17043.hic 138.9 Mb (ftp)(http) HIC
GSE268050_HIC17043_30.hic 132.3 Mb (ftp)(http) HIC
GSE268050_HIC17044.hic 158.9 Mb (ftp)(http) HIC
GSE268050_HIC17044_30.hic 149.9 Mb (ftp)(http) HIC
GSE268050_HIC17045.hic 121.6 Mb (ftp)(http) HIC
GSE268050_HIC17045_30.hic 116.8 Mb (ftp)(http) HIC
GSE268050_HIC17046.hic 114.3 Mb (ftp)(http) HIC
GSE268050_HIC17046_30.hic 110.1 Mb (ftp)(http) HIC
GSE268050_HIC17047.hic 140.5 Mb (ftp)(http) HIC
GSE268050_HIC17047_30.hic 133.7 Mb (ftp)(http) HIC
GSE268050_HIC17048.hic 100.5 Mb (ftp)(http) HIC
GSE268050_HIC17048_30.hic 97.3 Mb (ftp)(http) HIC
GSE268050_HIC17049.hic 100.1 Mb (ftp)(http) HIC
GSE268050_HIC17049_30.hic 96.8 Mb (ftp)(http) HIC
GSE268050_HIC17050.hic 69.1 Mb (ftp)(http) HIC
GSE268050_HIC17050_30.hic 68.6 Mb (ftp)(http) HIC
GSE268050_HIC17051.hic 66.6 Mb (ftp)(http) HIC
GSE268050_HIC17051_30.hic 66.4 Mb (ftp)(http) HIC
GSE268050_HIC17052.hic 126.9 Mb (ftp)(http) HIC
GSE268050_HIC17052_30.hic 121.6 Mb (ftp)(http) HIC
GSE268050_HIC17053.hic 64.7 Mb (ftp)(http) HIC
GSE268050_HIC17053_30.hic 64.6 Mb (ftp)(http) HIC
GSE268050_HIC17054.hic 108.1 Mb (ftp)(http) HIC
GSE268050_HIC17054_30.hic 104.3 Mb (ftp)(http) HIC
GSE268050_HIC17055.hic 81.7 Mb (ftp)(http) HIC
GSE268050_HIC17055_30.hic 79.9 Mb (ftp)(http) HIC
GSE268050_HIC17056.hic 67.7 Mb (ftp)(http) HIC
GSE268050_HIC17056_30.hic 67.4 Mb (ftp)(http) HIC
GSE268050_HIC17057.hic 69.5 Mb (ftp)(http) HIC
GSE268050_HIC17057_30.hic 68.9 Mb (ftp)(http) HIC
GSE268050_HIC17058.hic 66.9 Mb (ftp)(http) HIC
GSE268050_HIC17058_30.hic 66.6 Mb (ftp)(http) HIC
GSE268050_HIC17072.hic 294.8 Mb (ftp)(http) HIC
GSE268050_HIC17072_30.hic 267.9 Mb (ftp)(http) HIC
GSE268050_HIC17075.hic 309.7 Mb (ftp)(http) HIC
GSE268050_HIC17075_30.hic 281.8 Mb (ftp)(http) HIC
GSE268050_HIC17076.hic 312.2 Mb (ftp)(http) HIC
GSE268050_HIC17076_30.hic 284.8 Mb (ftp)(http) HIC
GSE268050_HIC17077.hic 310.5 Mb (ftp)(http) HIC
GSE268050_HIC17077_30.hic 283.2 Mb (ftp)(http) HIC
GSE268050_HIC17081.hic 402.9 Mb (ftp)(http) HIC
GSE268050_HIC17081_30.hic 364.8 Mb (ftp)(http) HIC
GSE268050_HIC17082.hic 266.9 Mb (ftp)(http) HIC
GSE268050_HIC17082_30.hic 243.8 Mb (ftp)(http) HIC
GSE268050_HIC17083.hic 257.2 Mb (ftp)(http) HIC
GSE268050_HIC17083_30.hic 235.5 Mb (ftp)(http) HIC
GSE268050_HIC17139.hic 204.5 Mb (ftp)(http) HIC
GSE268050_HIC17139_30.hic 188.7 Mb (ftp)(http) HIC
GSE268050_HIC17141.hic 221.0 Mb (ftp)(http) HIC
GSE268050_HIC17141_30.hic 203.6 Mb (ftp)(http) HIC
GSE268050_HIC17143.hic 176.7 Mb (ftp)(http) HIC
GSE268050_HIC17143_30.hic 161.9 Mb (ftp)(http) HIC
GSE268050_HIC17144.hic 163.8 Mb (ftp)(http) HIC
GSE268050_HIC17144_30.hic 152.7 Mb (ftp)(http) HIC
GSE268050_HIC17145.hic 183.7 Mb (ftp)(http) HIC
GSE268050_HIC17145_30.hic 171.3 Mb (ftp)(http) HIC
GSE268050_HIC17146.hic 208.5 Mb (ftp)(http) HIC
GSE268050_HIC17146_30.hic 193.3 Mb (ftp)(http) HIC
GSE268050_HIC17147.hic 219.5 Mb (ftp)(http) HIC
GSE268050_HIC17147_30.hic 203.5 Mb (ftp)(http) HIC
GSE268050_HIC17148.hic 173.5 Mb (ftp)(http) HIC
GSE268050_HIC17148_30.hic 163.1 Mb (ftp)(http) HIC
GSE268050_HIC17149.hic 129.5 Mb (ftp)(http) HIC
GSE268050_HIC17149_30.hic 123.8 Mb (ftp)(http) HIC
GSE268050_HIC17150.hic 186.0 Mb (ftp)(http) HIC
GSE268050_HIC17150_30.hic 174.8 Mb (ftp)(http) HIC
GSE268050_HIC17151.hic 153.4 Mb (ftp)(http) HIC
GSE268050_HIC17151_30.hic 145.5 Mb (ftp)(http) HIC
GSE268050_HIC17152.hic 201.1 Mb (ftp)(http) HIC
GSE268050_HIC17152_30.hic 185.6 Mb (ftp)(http) HIC
GSE268050_HIC17153.hic 184.8 Mb (ftp)(http) HIC
GSE268050_HIC17153_30.hic 172.2 Mb (ftp)(http) HIC
GSE268050_HIC17154.hic 214.1 Mb (ftp)(http) HIC
GSE268050_HIC17154_30.hic 198.2 Mb (ftp)(http) HIC
GSE268050_HIC17155.hic 215.3 Mb (ftp)(http) HIC
GSE268050_HIC17155_30.hic 200.3 Mb (ftp)(http) HIC
GSE268050_HIC17156.hic 144.3 Mb (ftp)(http) HIC
GSE268050_HIC17156_30.hic 137.4 Mb (ftp)(http) HIC
GSE268050_HIC17157.hic 167.3 Mb (ftp)(http) HIC
GSE268050_HIC17157_30.hic 157.9 Mb (ftp)(http) HIC
GSE268050_HIC17158.hic 130.1 Mb (ftp)(http) HIC
GSE268050_HIC17158_30.hic 124.8 Mb (ftp)(http) HIC
GSE268050_HIC17159.hic 150.9 Mb (ftp)(http) HIC
GSE268050_HIC17159_30.hic 143.6 Mb (ftp)(http) HIC
GSE268050_HIC17160.hic 110.9 Mb (ftp)(http) HIC
GSE268050_HIC17160_30.hic 107.0 Mb (ftp)(http) HIC
GSE268050_HIC17161.hic 121.9 Mb (ftp)(http) HIC
GSE268050_HIC17161_30.hic 117.2 Mb (ftp)(http) HIC
GSE268050_HIC17162.hic 78.0 Mb (ftp)(http) HIC
GSE268050_HIC17162_30.hic 76.5 Mb (ftp)(http) HIC
GSE268050_HIC17163.hic 74.7 Mb (ftp)(http) HIC
GSE268050_HIC17163_30.hic 73.6 Mb (ftp)(http) HIC
GSE268050_HIC17200.hic 274.4 Mb (ftp)(http) HIC
GSE268050_HIC17200_30.hic 250.5 Mb (ftp)(http) HIC
GSE268050_HIC17205.hic 278.9 Mb (ftp)(http) HIC
GSE268050_HIC17205_30.hic 254.8 Mb (ftp)(http) HIC
GSE268050_HS_ENCODE_corserved_loops_Loxafr3.0_HiC.bedpe.gz 176.8 Kb (ftp)(http) BEDPE
GSE268050_HS_ENCODE_corserved_loops_hg38.bedpe.gz 525.0 Kb (ftp)(http) BEDPE
GSE268050_HS_GSE63525_conserved_loops_bosTau9.bedpe.gz 614.0 Kb (ftp)(http) BEDPE
GSE268050_LAF1789_Loxafr3.0_HiC.hic 838.0 Mb (ftp)(http) HIC
GSE268050_LAF1789_Loxafr3.0_HiC_30.hic 743.0 Mb (ftp)(http) HIC
GSE268050_LAF1790_Loxafr3.0_HiC.hic 881.1 Mb (ftp)(http) HIC
GSE268050_LAF1790_Loxafr3.0_HiC_30.hic 780.9 Mb (ftp)(http) HIC
GSE268050_LA_HiCCUPS_loops_Loxafr3.0_HiC.bedpe.gz 211.8 Kb (ftp)(http) BEDPE
GSE268050_LA_HiCCUPS_loops_MamPri_ASM1433276v1_assisted_HiC.bedpe.gz 213.4 Kb (ftp)(http) BEDPE
GSE268050_LA_HiCCUPS_loops_MamPri_Loxafr3.0_assisted_HiC.bedpe.gz 208.1 Kb (ftp)(http) BEDPE
GSE268050_LA_SIP_loops_Loxafr3.0_HiC.bedpe.gz 58.6 Kb (ftp)(http) BEDPE
GSE268050_LA_mega_Loxafr3.0_HiC.hic 1.4 Gb (ftp)(http) HIC
GSE268050_LA_mega_Loxafr3.0_HiC_30.hic 1.2 Gb (ftp)(http) HIC
GSE268050_LA_mega_MamPri_ASM1433276v1_assisted_HiC.hic 1.4 Gb (ftp)(http) HIC
GSE268050_LA_mega_MamPri_ASM1433276v1_assisted_HiC_30.hic 1.2 Gb (ftp)(http) HIC
GSE268050_LA_mega_MamPri_Loxafr3.0_assisted_HiC.hic 1.3 Gb (ftp)(http) HIC
GSE268050_LA_mega_MamPri_Loxafr3.0_assisted_HiC_30.hic 1.2 Gb (ftp)(http) HIC
GSE268050_Loxafr3.0.hic 1.3 Gb (ftp)(http) HIC
GSE268050_Loxafr3.0.rawchrom.hic 1.3 Gb (ftp)(http) HIC
GSE268050_Loxafr3.0_HiC.assembly.txt.gz 26.4 Kb (ftp)(http) TXT
GSE268050_Loxafr3.0_HiC.fasta.gz 985.4 Mb (ftp)(http) FASTA
GSE268050_Loxafr3.0_HiC.refseq_annotations.bed.gz 2.2 Mb (ftp)(http) BED
GSE268050_Loxafr3.0_HiC.toga_annotations.bed.gz 2.1 Mb (ftp)(http) BED
GSE268050_Loxafr3.0_mock_HiC.assembly.txt.gz 24.5 Kb (ftp)(http) TXT
GSE268050_Loxafr3.0_mock_HiC.fasta.gz 985.4 Mb (ftp)(http) FASTA
GSE268050_Loxafr3.0_sub_HiC.assembly.txt.gz 24.6 Kb (ftp)(http) TXT
GSE268050_Loxafr3.0_sub_HiC.fasta.gz 985.4 Mb (ftp)(http) FASTA
GSE268050_MP_EtOH_Loxafr3.0_HiC.hic 119.5 Mb (ftp)(http) HIC
GSE268050_MP_EtOH_Loxafr3.0_HiC_30.hic 107.6 Mb (ftp)(http) HIC
GSE268050_MP_Loxafr3.0_HiC.hic 126.7 Mb (ftp)(http) HIC
GSE268050_MP_Loxafr3.0_HiC_30.hic 113.8 Mb (ftp)(http) HIC
GSE268050_MP_MamPri_ASM1433276v1_assisted_HiC.hic 130.3 Mb (ftp)(http) HIC
GSE268050_MP_MamPri_ASM1433276v1_assisted_HiC_30.hic 118.2 Mb (ftp)(http) HIC
GSE268050_MP_MamPri_Loxafr3.0_assisted_HiC.hic 128.1 Mb (ftp)(http) HIC
GSE268050_MP_MamPri_Loxafr3.0_assisted_HiC_30.hic 117.4 Mb (ftp)(http) HIC
GSE268050_MP_nonEtOH_Loxafr3.0_HiC.hic 53.4 Mb (ftp)(http) HIC
GSE268050_MP_nonEtOH_Loxafr3.0_HiC_30.hic 50.9 Mb (ftp)(http) HIC
GSE268050_MP_skin_CRUSH_Loxafr3.0_HiC.bedgraph.gz 531.3 Kb (ftp)(http) BEDGRAPH
GSE268050_MamPri_ASM1433276v1_assisted.hic 435.4 Mb (ftp)(http) HIC
GSE268050_MamPri_ASM1433276v1_assisted.rawchrom.hic 427.7 Mb (ftp)(http) HIC
GSE268050_MamPri_ASM1433276v1_assisted_HiC.fasta.gz 867.2 Mb (ftp)(http) FASTA
GSE268050_MamPri_Loxafr3.0_assisted.hic 424.4 Mb (ftp)(http) HIC
GSE268050_MamPri_Loxafr3.0_assisted.rawchrom.hic 423.3 Mb (ftp)(http) HIC
GSE268050_MamPri_Loxafr3.0_assisted_HiC.fasta.gz 903.3 Mb (ftp)(http) FASTA
GSE268050_MamPri_Loxafr3.0_assisted_HiC.toga_annotations.bed.gz 2.1 Mb (ftp)(http) BED
GSE268050_MiChroM_Loxafr3.0_HiC.hic 76.8 Mb (ftp)(http) HIC
GSE268050_PaleoHi-C_extended_reference.hic 7.0 Kb (ftp)(http) HIC
GSE268050_RMSD_000nm.hic 384.8 Kb (ftp)(http) HIC
GSE268050_RMSD_010nm.hic 350.5 Kb (ftp)(http) HIC
GSE268050_RMSD_025nm.hic 341.9 Kb (ftp)(http) HIC
GSE268050_RMSD_050nm.hic 323.4 Kb (ftp)(http) HIC
GSE268050_RMSD_100nm.hic 287.4 Kb (ftp)(http) HIC
GSE268050_RMSD_200nm.hic 236.3 Kb (ftp)(http) HIC
GSE268050_Woolly_Mammoth_Direct_Inv.sw 1.1 Gb (ftp)(http) SW
GSE268050_Woolly_Mammoth_MiChroM.sw 30.1 Gb (ftp)(http) SW
GSE268050_Yuka.aca.hic 98.1 Kb (ftp)(http) HIC
GSE268050_Yuka_Loxafr3.0_HiC.hic 31.2 Mb (ftp)(http) HIC
GSE268050_Yuka_Loxafr3.0_HiC_30.hic 31.0 Mb (ftp)(http) HIC
GSE268050_direct_inversion_chr10_Loxafr3.0_HiC.hic 3.5 Mb (ftp)(http) HIC
GSE268050_readme.xlsx 14.9 Kb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap