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| Status |
Public on Aug 01, 2011 |
| Title |
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression profiling was used to investigate the relationship between human cord blood hematopoietic stem cells (HSC) and multipotent progenitors described in the study. Genes more highly expressed in HSC may be associated with stem cell function and self-renewal.
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| |
|
| Overall design |
Total RNA was obtained from flow-sorted populations based on the cell surface expression of CD34, CD38, CD45RA, Thy1, and CD49f.
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| |
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| Contributor(s) |
Notta F, Doulatov S, Laurenti E, Poeppl A, Jurisica I |
| Citation(s) |
21737740 |
| Submission date |
May 06, 2011 |
| Last update date |
Aug 16, 2018 |
| Contact name |
Sergei Doulatov |
| E-mail(s) |
sdoulato@uhnres.utoronto.ca
|
| Organization name |
Campbell Family Institute for Cancer Research/Ontario Cancer Institute
|
| Department |
Division of Stem Cell and Developmental Biology
|
| Lab |
John E Dick
|
| Street address |
101 College Street, TMDT 8-301
|
| City |
Toronto |
| State/province |
Ontario |
| ZIP/Postal code |
M5G 1L7 |
| Country |
Canada |
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| Platforms (1) |
| GPL6947 |
Illumina HumanHT-12 V3.0 expression beadchip |
|
| Samples (9)
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| Relations |
| BioProject |
PRJNA140365 |
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