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| Status |
Public on Feb 22, 2012 |
| Title |
Expression data from normal thymocytes, 24 day pre-tumor Dnmt3b-deficient thymocytes, Wild-Type Tumors, and Dnmt3b-deficient Tumors |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Dnmt3b is a DNA methytransferase which is an enzyme that methylated genomic DNA which contributes to genomic stability and transcriptional regulation.
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| Overall design |
We genetically inactivated Dnmt3b in the hematopoeitic compartment in the context of MYC overexpression and analysed the resulting thymic lymphomas.
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| Contributor(s) |
Opavsky R, Hlady R, Opavska J, Novakova S |
| Citation(s) |
22133874 |
| Submission date |
Jun 21, 2011 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Ryan Hlady |
| E-mail(s) |
rhlady@unmc.edu
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| Phone |
4025595544
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| Organization name |
UNMC
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| Department |
Eppley
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| Lab |
Rene Opavsky
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| Street address |
985950 DRC II 4020
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| City |
Omaha |
| State/province |
Nebraska |
| ZIP/Postal code |
68198 |
| Country |
USA |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (11)
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| GSM745872 |
Normal Thymocytes, biological replicate 1 |
| GSM745873 |
Normal Thymocytes, biological replicate 2 |
| GSM745874 |
Normal Thymocytes, biological replicate 3 |
| GSM745875 |
Wild-Type Lymphoma, biological replicate 1 |
| GSM745876 |
Wild-Type Lymphoma, biological replicate 2 |
| GSM745877 |
Wild-Type Lymphoma, biological replicate 3 |
| GSM745878 |
Dnmt3b-deficient Lymphoma, biological replicate 1 |
| GSM745879 |
Dnmt3b-deficient Lymphoma, biological replicate 2 |
| GSM745880 |
Dnmt3b-deficient Lymphoma, biological replicate 3 |
| GSM745881 |
24 day pre-tumor Dnmt3b-deficient thymocytes, biological replicate 1 |
| GSM745882 |
24 day pre-tumor Dnmt3b-deficient thymocytes, biological replicate 2 |
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| Relations |
| BioProject |
PRJNA144039 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE30126_RAW.tar |
39.8 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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