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| Status |
Public on Mar 31, 2012 |
| Title |
Expression data from Drosophila Btk29A mutant and revertant neuronal tissue |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by array
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| Summary |
In Drosophila melanogaster, Btk29A displays a dynamic pattern of expression through the embryonic to adult stages. Complete loss-of function of both splice-forms is lethal, whereas selective absence of the type 2-form reduces the adult lifespan of the fly and causes male genitalial developmental abnormalities.
Here, we investigated the role of Btk29A type 2 on a transcriptomic level in the larvae CNS and adult heads. We used samples either selectively defective in Btk29A type 2 (Btk29AficP) or flies were the Btk29A type 2 gene has been reintroduced (ficExc.1-16).
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| Overall design |
Adult heads and larvae CNS were dissected for RNA extraction and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Nawaz H, Smith CI, Lindvall JM |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jul 13, 2011 |
| Last update date |
Aug 28, 2018 |
| Contact name |
Hossain Nawaz |
| E-mail(s) |
hossain.nawaz@ki.se
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| Phone |
+46858583806
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| Fax |
+46858583650
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| Organization name |
Karolinska Institutet
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| Department |
LABMED
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| Lab |
KFC/MCG Lab 514
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| Street address |
Hälsovägen 7
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| City |
Huddinge |
| State/province |
Stockholm |
| ZIP/Postal code |
14186 |
| Country |
Sweden |
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| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
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| Samples (12)
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| GSM759719 |
FicP larvae CNS, biological rep1 |
| GSM759720 |
FicP larvae CNS, biological rep2 |
| GSM759721 |
FicP larvae CNS, biological rep3 |
| GSM759722 |
Revertant adult head, biological rep1 |
| GSM759723 |
Revertant adult head, biological rep2 |
| GSM759724 |
Revertant adult head, biological rep3 |
| GSM759725 |
Revertant larvae CNS, biological rep1 |
| GSM759726 |
Revertant larvae CNS, biological rep2 |
| GSM759727 |
Revertant larvae CNS, biological rep3 |
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| Relations |
| BioProject |
PRJNA144577 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE30627_RAW.tar |
24.1 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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